20.500.12556/RUL-151616 Cardiac electromechanical activity in healthy cats and cats with cardiomyopathies Optimal heart function depends on perfect synchronization between electrical and mechanical activity. In this pilot study, we aimed to investigate the electromechanical activity of the heart in healthy cats and cats with cardiomyopathy with phonocardiography (PCG) synchronized to an electrocardiography (ECG) pilot device. We included 29 cats (12 healthy cats and 17 cats diagnosed with cardiomyopathy) and performed a clinical examination, PCG synchronized with ECG and echocardiography. We measured the following durations with the pilot PCG device synchronized with ECG: QRS (ventricular depolarization), QT interval (electrical systole), QS1 interval (electromechanical activation time (EMAT)), S1S2 (mechanical systole), QS2 interval (electrical and mechanical systole) and electromechanical window (end of T wave to the beginning of S2). The measured parameters did not differ between healthy cats and cats with cardiomyopathy; however, in cats with cardiomyopathy, EMAT/RR, QS2/RR and S1S2/RR were significantly longer than in healthy cats. This suggests that the hypertrophied myocardium takes longer to generate sufficient pressure to close the mitral valve and that electrical systole, i.e., depolarization and repolarization, and mechanical systoles are longer in cats with cardiomyopathy. The PCG synchronized with the ECG pilot device proved to be a valuable tool for evaluating the electromechanical activity of the feline heart. electrocardiography phonocardiography echocardiography cardiomyopathies cats true false true Angleški jezik Ni določen Članek v reviji 2023-10-12 13:46:37 2023-10-12 13:46:40 2023-10-16 08:50:47 0000-00-00 00:00:00 2023 0 0 13 str. issue 19, [art. no.] 8336 Vol. 29 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.09:616 1424-8220 10.3390/s23198336 167620099 Cardiac-Domanjko.pdf Cardiac-Domanjko.pdf 1 A68DAB7A839E6B0CED13E80C05191B45 f4ac82e24d5c69c6e85f25a074f391116bc6e79777c265cba2a44fbce20e0de4 205f9202-68f6-11ee-a464-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=176629 https://www.mdpi.com/1424-8220/23/19/8336 1 027dc86c-68f5-11ee-a464-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=176627 Veterinarska fakulteta 0 0 0