20.500.12556/RUL-147270 Ossification of ligamentum flavum related to progressive thoracic myelopathy and acute paraplegia in a Central-European male with a thoracic kyphoscoliosis The ossification of the ligamentum flavum (OLF) presents a significant risk factor in the development of spinal cord compression in the (lower) thoracic spine, particularly in eastern Asian elderly males. The definite causes for OLF have not yet been fully uncovered, whereby age, genetics, metabolic disorders and mechanical stress are deemed among the most plausible pathophysiological factors in OLF. Spinal deformities (mostly kyphotic) are associated with an excess in tensile forces, which may lead to hypertrophy and OLF. This unique case of OLF-related acute paraplegia and progressive thoracic myelopathy in a Central-European male patient may indicate the role of a (kyphoscoliotic) spinal deformity in the initiation and progression of the OLF-related (thoracic) myelopathy. Promptly initiated surgical decompression and (partial) deformity correction may, along with proper subsequent intradisciplinary rehabilitation process, greatly improve the clinical outcome post-treatment, especially in terms of quality of life and residual pain. ossification of ligamentum flavum thoracic myelopathy thoracic kyphoscoliosis trauma orthopaedic surgery okostenitev rumenega ligamenta torakalna mielopatija torakalna kifoskolioza true false true Angleški jezik Slovenski jezik Članek v reviji 2023-06-28 11:11:29 2023-06-28 11:11:33 2023-06-29 03:40:34 0000-00-00 00:00:00 2023 0 0 4 str. iss. 2, art. rjad070 Vol. 2023 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 617.3 2042-8812 10.1093/jscr/rjad070 143666435 rjad070.pdf rjad070.pdf 1 F6D2F867F6F252628C3EA815BC0DA449 c59945dc1478efe26c2cd579f71964e95351b878dbae30aa8a580907c75c3f5e c5638de9-1593-11ee-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=170792 https://academic.oup.com/jscr/article/2023/2/rjad070/7055696 1 660f5dd9-1593-11ee-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=170790 Medicinska fakulteta 0 0 0