20.500.12556/RUL-144814 Non-contact monitoring of the depth temperature profile for medical laser scanning technologies Medical treatments such as high-intensity focused ultrasound, hyperthermic laser lipolysis or radiofrequency are employed as a minimally invasive alternatives for targeted tissue therapies. The increased temperature of the tissue triggers various thermal effects and leads to an unavoidable damage. As targeted tissues are generally located below the surface, various approaches are utilized to prevent skin layers from overheating and irreparable thermal damages. These procedures are often accompanied by cooling systems and protective layers accounting for a non-trivial detection of the subsurface temperature peak. Here, we show a temperature peak estimation method based on infrared thermography recording of the surface temperature evolution coupled with a thermal-diffusion-based model and a time-dependent data matching algorithm. The performance of the newly developed method was further showcased by employing hyperthermic laser lipolysis on an ex-vivo porcine fat tissue. Deviations of the estimated peak temperature remained below 1 °C, as validated by simultaneous measurement of depth temperature field within the tissue. Reconstruction of the depth profile shows a good reproducibility of the real temperature distribution with a small deviation of the peak temperature position. A thermal camera in combination with the time-dependent matching bears the scope for non-contact monitoring of the depth temperature profile as fast as 30 s. The latest demand for miniaturization of thermal cameras provides the possibility to embed the model in portable thermal scanners or medical laser technologies for improving safety and efficiency. thermography depth temperatur profile heat transfer in biological tissue biomedical engineering engineering termografija temperaturni profil prenos toplote v tkivu true false true Angleški jezik Slovenski jezik Članek v reviji 2023-03-14 14:12:58 2023-03-14 14:13:03 2023-03-15 03:30:56 0000-00-00 00:00:00 2020 0 0 10 str. Vol. 10, art. 20242 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 61:543.572.3(045) 2045-2322 10.1038/s41598-020-77283-9 39682307 s41598-020-77283-9.pdf s41598-020-77283-9.pdf 1 7F950041A73A5A4E19845B3A5D2DADEC f4d408fa971876f8b160f8ef299cdb52fa386769bf09ecc3e77df915d4ea287d 40285f95-c26a-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=167352 https://www.nature.com/articles/s41598-020-77283-9 1 e69c885f-c269-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=167351 Fakulteta za strojništvo 0 0 0