20.500.12556/RUL-144724 Review article: structural brain alterations in prelingually deaf Functional studies show that our brain has a remarkable ability to reorganize itself in the absence of one or more sensory modalities. In this review, we gathered all the available articles investigating structural alterations in congenitally deaf subjects. Some concentrated only on specific regions of interest (e.g., auditory areas), while others examined the whole brain. The majority of structural alterations were observed in the auditory white matter and were more pronounced in the right hemisphere. A decreased white matter volume or fractional anisotropy in the auditory areas were the most common findings in congenitally deaf subjects. Only a few studies observed alterations in the auditory grey matter. Preservation of the grey matter might be due to the cross-modal plasticity as well as due to the lack of sensitivity of methods used for microstructural alterations of grey matter. Structural alterations were also observed in the frontal, visual, and other cerebral regions as well as in the cerebellum. The observed structural brain alterations in the deaf can probably be attributed mainly to the cross-modal plasticity in the absence of sound input and use of sign instead of spoken language. brain prelingually deafness structure plasticity hearing loss možgani gluhost struktura true false true Angleški jezik Slovenski jezik Članek v reviji 2023-03-09 14:01:54 2023-03-09 14:01:58 2023-03-20 12:47:54 0000-00-00 00:00:00 2020 0 0 22 str. Vol. 220, art. 117042 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.8 1095-9572 10.1016/j.neuroimage.2020.117042 23619331 1-s2.0-S1053811920305280-main.pdf 1-s2.0-S1053811920305280-main.pdf 1 29A7A98E0CAF01207FB3BAAB443944E9 d0be524e03ece49279797e1778a29d458ee2d4bdc62d47560c5e5b73e5a56071 b2169b0a-be7a-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=167204 https://www.sciencedirect.com/science/article/pii/S1053811920305280 0 894e9619-be7a-11ed-a314-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=167203 Medicinska fakulteta 0 0 0