20.500.12556/RUL-144471 Autologous platelet and extracellular vesicle-rich plasma as therapeutic fluid a review The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has been explored in many medical fields with the aim to benefit from its healing potential. In parallel, efforts are being invested to understand the function and dynamics of PVRP that is complex in its composition and interactions. Some clinical evidence reveals beneficial effects of PVRP, while some report that there were no effects. To optimize the preparation methods, functions and mechanisms of PVRP, its constituents should be better understood. With the intention to promote further studies of autologous therapeutic PVRP, we performed a review on some topics regarding PVRP composition, harvesting, assessment and preservation, and also on clinical experience following PVRP application in humans and animals. Besides the acknowledged actions of platelets, leukocytes and different molecules, we focus on extracellular vesicles that were found abundant in PVRP. platelet-rich plasma platelets centrifugation extracellular vesicles small cellular particles wound healing regeneration fresh-frozen plasma intercellular signaling peptides and proteins plazma bogata s trombociti trombociti centrifugiranje zunajcelični vezikli majhni celični delci celjenje ran regeneracija sveže zamrznjena plazma medcelični signalni peptidi in proteini true false true Angleški jezik Ni določen Članek v reviji 2023-02-23 10:58:05 2023-02-23 10:58:06 2023-02-24 03:45:01 0000-00-00 00:00:00 2023 0 0 39 str. no. 4, art.3420 Vol. 24 Feb. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-02-08 577:616.15 1422-0067 10.3390/ijms24043420 142752771 Troha-2023-Autologous-platelet-and-extracellul.pdf Troha-2023-Autologous-platelet-and-extracellul.pdf 1 EC2CE1D9AE228F9838A9416D567B56E1 17ed1658e2485d886e0afa6221f07d04acab5379446ef3bf90fcb0100d4bf1d6 c270bb54-b360-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166796 https://www.mdpi.com/1422-0067/24/4/3420 1 3af04a4b-b360-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166795 Zdravstvena fakulteta Medicinska fakulteta Fakulteta za elektrotehniko Biotehniška fakulteta Fakulteta za kemijo in kemijsko tehnologijo 0 0 0