20.500.12556/RUL-144177 Acute moderate-intensity exercise increases total antioxidant capacity and anti-inflammatory responses in competitive cyclists the role of adiponectin High-intensity exercise can elicit acute changes in the biochemical and physiological processes in the body of an athlete, including increased oxidative stress and inflammation. The purpose of this study was to explore the effect of acute moderate-intensity exercise on total antioxidant capacity (TAC) and serum levels of anti-inflammatory adiponectin (APN), and inflammatory markers in competitive cyclists. Ten male cyclists (age 15–26 years, body mass index 19.4–24.7 kg/m$^2$) participated in this study. Each subject performed the maximal oxygen uptake test (VO$_{2peak}$) and completed a 10-min cycling exercise at a workload of 50% of the peak of VO$_{2peak}$. Blood samples were collected on three different occasions: after an overnight fasting and at the exercise workloads of 50% and 100% VO$_{2peak}$. We measured APN, TAC, inflammatory markers as well as assessed nutrient and energy intake for each participant. Baseline concentration of serum APN (10.92µg/mL) significantly increased at 50% and at 100% VO$_{2peak}$. In addition, TAC also increased after acute exercise (0.079 vs 0.093 nmol/µL). The concentration of APN at 50% VO$_{2peak}$ positively correlated with the CRP (r = 0.640, p = 0.046) and negatively correlated with TNF-α (r = −0.696, p = 0.025). This test showed that short (10min) and medium-intensity (50% VO$_{2peak}$) exercise activity in trained athletes evoked beneficial antioxidant and anti-inflammatory responses. Importantly, this response correlates with the increase in APN levels thereby showing that highly trained individuals have beneficial responses originating from adipose tissue. Our observations show that a short training at moderate activity can be an important preservative strategy during the recovery training period. adiponectin athlete cycling inflammation oxidative stress TAC adiponektin atleti kolesarstvo vnetje oksidativni stres celokupni antioksidativni potencial true false true Angleški jezik Slovenski jezik Članek v reviji 2023-02-02 14:16:07 2023-02-02 14:16:08 2023-02-04 03:19:58 0000-00-00 00:00:00 2021 0 0 11 str. Vol. 19 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 577.17 2058-7392 10.1177/2058739221998890 55214595 2058739221998890.pdf 2058739221998890.pdf 1 598F9A19DDF1F0C27B0A69B4D887AB69 b5daf069b95adbb32235381133f88628c3cf8f6deabc35c2a866754d59c73ebc a1b6eef8-a2fb-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166366 https://journals.sagepub.com/doi/10.1177/2058739221998890 0 8775b24b-a2fb-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166365 Medicinska fakulteta 0 0 0