20.500.12556/RUL-144173 Literature review and our experience with bleomycin-based electrochemotherapy for cutaneous vulvar metastases from endometrial cancer Endometrial carcinoma is the most common gynecological malignancy and the fifth most common malignancy in women. The worldwide incidence is 15.9 new cases per 100,000 women per year, and the incidence in Europe is 22.7 new cases. Minority of cases are diagnosed at an advanced stage of the disease. Cutaneous metastases are very rare with a prevalence of 0.8%. If cutaneous metastases are present, the prognosis is poor with an overall survival of up to 12 months. In this review, we presented clinical data on treatment of gynecological cancers with electrochemotherapy, with focus on treatment of cutaneous vulvar metastases from endometrial cancer. Further, we present our data on the case of a 64-year-old woman with recurrent endometrial adenocarcinoma with vulvar skin metastases. Treatment of endometrial carcinoma metastases is multimodal with surgery, chemotherapy, radiotherapy and hormone treatment. There is still no consensus about the specific treatment of cutaneous metastases from endometrial cancer, in particular in order to release symptoms. Electrochemotherapy may be a treatment option to reduce pain and bleeding and a safe option to treat multiple skin metastases. electrochemotherapy endometrial cancer cutaneous metastases skin metastases bleomycin elektrokemoterapija rak endometrija metastaze na koži bleomicin true false true Angleški jezik Slovenski jezik Članek v reviji 2023-02-02 13:12:30 2023-02-02 13:12:36 2023-02-04 03:19:03 0000-00-00 00:00:00 2021 0 0 6 str. Vol. 20 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.1 1533-0338 10.1177/15330338211010134 61008387 15330338211010134.pdf 15330338211010134.pdf 1 FBBF2C5F859441E71CE3FE71403CF389 d4a683a994d7c16781c2fd6bae51640c14a147fb7aa7337724cd921a4a9a5537 e81458a7-a2f2-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166356 https://journals.sagepub.com/doi/10.1177/15330338211010134 0 bc5b2a69-a2f2-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166355 Medicinska fakulteta Fakulteta za farmacijo Zdravstvena fakulteta 0 0 0