20.500.12556/RUL-144166 Radiologic evaluation of portosystemic shunts in humans and small animals review of the literature with clinical case reports The portal venous system is a network of vessels that carry blood from the capillary beds of the major abdominal organs to the liver. During embryology, the portal venous system can develop aberrantly, leading to vascular connections between the portal and systemic venous circulation known as portosystemic shunts. The purpose of this comparative review with a few short representative case reports was to present the similarities and differences in portosystemic shunts in humans and small animals and their radiologic evaluation. Aberrant vascular connections between the portal and systemic venous circulation enable portal blood to bypass metabolism and detoxification in the liver, leading to significant clinical implications. Portosystemic shunts are very rare in humans, but these connections are much more common in small animals, affecting up to 0.6% of small animals. Portosystemic shunts can be congenital or acquired and are divided into intrahepatic and extrahepatic types. Because of its ability to accurately assess abdominal structures, large vessels, and their flow dynamics without anesthesia, ultrasonography has become the first imaging modality employed for the diagnostic evaluation of portosystemic shunts in both humans and small animals. This is usually followed by contrast-enhanced computed tomographic angiography in order to better define the exact shunt anatomy and to plan treatment. It is important to understand the embryology, anatomy, pathology, and pathophysiology of portosystemic shunts in order to understand the findings of radiologic imaging and to initiate appropriate treatment. portosystemic shunt ultrasonography computational tomographic angiography portosistemski obvod ultrazvok računalniška tomografska angiografija true false true Angleški jezik Slovenski jezik Članek v reviji 2023-02-02 10:51:32 2023-02-02 10:51:36 2023-02-04 03:14:56 0000-00-00 00:00:00 2023 0 0 Str. 1-15 iss. 3, [article no.] 482 Vol. 13 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-01-01 616-07 2075-4418 10.3390/diagnostics13030482 139864835 diagnostics-13-00482-1.pdf diagnostics-13-00482-1.pdf 1 BE8DD9594D619F8B3A8A847EE1DF99C9 2b6c363ceba1cd5c57a69ed7c84748afa3438b815ac42b15240c224e03d2372c c412e7d2-a2df-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166337 https://www.mdpi.com/2075-4418/13/3/482 1 e5839a7e-a2de-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=166336 Veterinarska fakulteta Medicinska fakulteta 0 0 0