20.500.12556/RUL-143694 Scanning electron microscope images of HUVEC cells treated with materials used for processing of orthopaedic and dental Implants Use of orthopedic implants (OI) and dental implants (DI) is increasing due to obesity and ageing of the population. To increase the bio-functionality of metallic biomaterials, used for OI and DI, it is important to modify their surface composition, roughness, and structure without altering their mechanical properties. Different materials, such as minerals and inorganic compounds are used for coating OI and DI, however, they may cause response of the cells that are in contact with them in the body. To optimize the use of the materials in implant design, it is of interest to study the effect of the materials on cells. Here we present observations of micron-sized particles of milled Al2O3, TiO2 and hydroxyapatite (HA) on human umbilical vein endothelial cells (HUVEC) by scanning electron microscope. We observed morphological changes of the cells – budding of the cell membrane. Comparing to the control, more cells were detached from the glass they were grown on, indicating possibility of increased cell death or inability of the cells to attach to the surface. Described changes can be due to oxidative stress and inflammatory response of the treated cells. orthopedic implants inorganic coatings dental implants in vitro cell lines inflammatory response oxidative stress ortopedski vsadki anorganski premazi zobni vsadki in vitro celične linije vnetni odziv oksidativni stres true false true Angleški jezik Slovenski jezik Neznano 2023-01-09 10:17:46 2023-01-09 10:17:47 2023-01-10 03:29:54 0000-00-00 00:00:00 2022 0 0 Str. 97-101 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 615.4:577 10.55295/PSL.2022.D14 122718723 117944067 RAZ_Jan_Zala_2022.pdf RAZ_Jan_Zala_2022.pdf 1 6EB088707EE8F45A6644EA922518D6F7 a758f57f4302944b1f2780f5a608916c09715e78cde7c4b7965a8a2ee3039082 570e551f-8ffe-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=165557 Zdravstvena fakulteta Biotehniška fakulteta 0 0 0