20.500.12556/RUL-143675 General antidepressants prescribing trends 2009–2018 in Slovenia a cross-sectional retrospective database study Background: Antidepressants are one of the most frequently prescribed groups of medications. The aim of the study was to evaluate the prevalence and patterns of antidepressants prescribed between 2009 and 2018 in Slovenia in different patient-age groups. Methods: This retrospective cross-sectional study performed a nationwide database analysis of all outpatient antidepressant prescriptions based on Slovenian health claims data. Prevalence was defined as number of recipients prescribed at least one antidepressant per 1000 inhabitants. Antidepressant consumption was presented as total dispensed defined daily doses per year. Results: In 2018, 147,300 patients were prescribed at least one antidepressant. The prevalence had increased by 16% in ten years and by 7.6% in age standardised data. The largest increase in prevalence was seen in the oldest patients (>80 years, 25% increase); of these, antidepressants are now prescribed to 1 in 4. Use of antidepressants had increased by 38%, suggesting longer treatment duration, increase in dose prescribed or both. SSRIs (selective serotonin reuptake inhibitors) were the most prescribed antidepressants (70% share), with escitalopram and sertraline the most commonly prescribed antidepressants. Conclusion: The prevalence of antidepressant prescribing and antidepressant consumption is increasing, mainly due to the population ageing and the increasing prescribing in elderly patients. antidepressants prevalence drug utilisation elderly patients antidepresivna zdravila razširjenost uporaba zdravil starejši bolniki true false true Angleški jezik Slovenski jezik Članek v reviji 2023-01-06 16:06:47 2023-01-06 16:06:52 2023-01-07 03:34:15 0000-00-00 00:00:00 2022 0 0 Str. 401-405 no. 4 Vol. 26 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 615.214.3-056.24-053.88 1365-1501 10.1080/13651501.2022.2057331 104861443 General_antidepressants_prescribing_trends_2009_2018_in_Slovenia_a_cross_.pdf General_antidepressants_prescribing_trends_2009_2018_in_Slovenia_a_cross_.pdf 1 698CBACA75ED41BE7D27F31DD60ED77F 5966092af77ba861943aad558a147a43c25472449343814cc482eb05088a8ebd 3c1593bc-8dd4-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=165531 https://www.tandfonline.com/doi/full/10.1080/13651501.2022.2057331 1 89334c1a-8dd3-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=165530 Fakulteta za farmacijo 0 0 0