20.500.12556/RUL-142233 Učinek sirupa s kvasnim pripravkom in vitaminom C na potek prehlada in gripe pri zdravih otrocih Effects of syrup with yeast preparation and vitamin C on the course of common cold or influenza in generally healthy children Učinkovanje kvasovk Saccharomyces cerevisiae na imunski sistem in pojav epizod prehladov in gripe je aktualen raziskovalni problem. V raziskavi smo preverili, ali je pri sicer zdravih otrocih, ki redno uživajo sirup iz pekovskih kvasovk z vitaminom C, odpornost proti prehladu in gripi večja. Obenem smo preiskovali vpliv kvasnega pripravka z vitaminom C na porast izločevalnega imunoglobulina A (S-IgA) v slini otrok. Višje vrednosti S-IgA so v prejšnjih raziskavah povezali z manjšo pojavnostjo epizod prehlada in gripe. Izvedli smo s placebom nadzorovano dvojno slepo raziskavo s kvasnim pripravkom in vitaminom C, kontrolni skupini smo kot placebo odmerjali samo vitamin C. Rezultati raziskave niso pokazali vpliva sirupa s kvasnim pripravkom in vitaminom C na pojav epizod prehlada in gripe. Prav tako kvasni pripravek ni vplival na porast izločevalnega imunoglobulina A v slini. Naša raziskava ni pokazala ugodnega vpliva kvasovk Saccharomyces cerevisiae na odpornost otrok proti prehladu. The effect of Saccharomyces cerevisiae on the immune system and the occurrence of cold and flu episodes is a current research problem. In our study, we focused on the issue of better resistance to colds and flu in otherwise healthy children who regularly consume baker's yeast syrup with vitamin C. At the same time, we investigated the effect of vitamin C yeast preparation on the increase of excretory immunoglobulin A (S-IgA) in saliva of the children. Higher S-IgA levels have been associated in previous studies with a lower incidence of cold and flu episodes. A placebo-controlled double-blind study of syrup with yeast and vitamin C was performed, and only vitamin C was administered to the control group as placebo. The results of the study did not show the effect of yeast and vitamin C syrup on the occurrence of cold and flu episodes. Also, the yeast preparation did not affect the increase in excretory immunoglobulin A in saliva. Our study did not show a positive effect of Saccharomyces cerevisiae on children’s resistance to colds. prehranska dopolnila kvasni pripravek Saccharomyces cerevisae vitamin C imunomodulator imunost imunski sistem imunoglobulin A gripa prehlad otroci dvojno slepa placebo proba food supplements yeast preparation saccharomyces cerevisae vitamin c immunomodulator immunity immune system immunoglobulin a influenza common cold children double blind placebo trial true false false [J. Primc] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2022-10-27 07:15:59 2022-10-27 07:16:03 2022-11-03 08:06:35 0000-00-00 00:00:00 2022 0 Ljubljana 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 612.017:615.015:616.9-097 213893 127806723 24428.pdf 24428.pdf 1 3277214D4703D3CAE53BFBCD69585FCA 8e2c03ef74122c75f77af26f0cde073e135ba80ac0fd5801b2b874b306d032d4 6161efae-55b6-11ed-9c94-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=163531 Biotehniška fakulteta 0 0 0