20.500.12556/RUL-140116 Vzroki, oblike in odkrivanje primarne imunske pomankljivosti Causes, types and detection of primary immunodeficiency V delu je predstavljen pojem imunska pomanjkljivost. Ker gre za širok spekter bolezenskih stanj, je v delu podrobneje opisan sklop primarnih imunskih pomanjkljivosti. Te namreč med seboj zaradi lažje preglednosti ločimo v devet podkategorij. Kombinirane T-celične in B-celične pomanjkljivosti, motnje v koncentraciji serumskih protiteles, bolezni imunske regulacije, okvare koncentracije in/ali funkcije fagocitnih celic, okvare signalnih molekul prirojenega imunskega odziva, avtovnetne bolezni, deficiti komplementa, sindromske primarne imunske pomanjkljivosti in fenokopije primarnih imunskih pomanjkljivosti. Ker imajo pomanjkljivosti velik vpliv na vsakodnevno življenje bolnika, je zelo pomembno, da jih čimprej odkrijemo. V ta namen imamo razvitih veliko testov, ki omogočajo zaznavo posameznih pomanjkljivosti. Z njihovo pomočjo lahko posamezniku omogočimo najboljšo obliko zdravljenja, prilagojeno njegovi imunski pomanjkljivosti. In this work I present the concept of immunodeficiency. The concept includes a wide specter of illnesses, however here the focus is on primary immunodeficiency. Since this type of immunodeficiency still includes many different illnesses, there exist nine subcatagories in which we further devide the condition. Predominantly antibody deficiencies T-cell immunodeficiencies or combined immunodeficiencies Syndromic immunodeficiencies Complement defects Phagocytic defects Defects of innate immunity Diseases of immune dysregulation Autoinflammatory disorders Phenocopies of Primary immunodeficiency. The immunodeficiency plays a huge roll in everyday life of the patient, therefor we ought to discover them as early as possible. For this purpose, today, we have many tests at our disposal. With them we can discover specific immunodeficiency, which helps us chose the best treatment for the patient. primarna imunska pomanjkljivost oblike primarne imunske pomanjkljivosti limfociti diagnostični testi imunoglobulini primary immunodeficiency types of primary immunodeficiency lymphocytes diagnostic immunoglobulins true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2022-09-11 07:17:46 2022-09-11 07:17:48 2022-10-12 14:53:47 0000-00-00 00:00:00 2022 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 210208 125349123 26365.pdf 26365.pdf 1 57455B0829EC99F806B2942A08A17CE7 afcb88f2cb000ff8bcf4b1041f35f8f7addb48c3c394c858d4ce0ee55622392e 0429c9fc-3191-11ed-92af-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=160787 Biotehniška fakulteta 0 0 0