20.500.12556/RUL-138881 Induced pluripotent stem cell (iPSC) line MLi004-A derived from a patient with recessive dystrophic epidermolysis bullosa (RDEB) We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier function. The characterization of the MLi004-A cell line consisted of molecular karyotyping, next-generation sequencing of the COL7A1 alleles, plu-ripotency and differentiation potentials testing by immunofluorescence of associated markers in vitro. The MLi004-A line has been also tested for ability to differentiate into fibroblasts. stem cell epidermolysis collagen VII recessive dystrophic EB iPSC line pluripotency fibroblast keratinocyte matične celice epidermoliza kolagen VII true false true Angleški jezik Slovenski jezik Članek v reviji 2022-08-24 11:04:02 2022-08-24 11:04:05 2022-09-15 04:17:20 0000-00-00 00:00:00 2021 0 0 5 str. Vol. 55, art. 102463 Aug. 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 61 1876-7753 10.1016/j.scr.2021.102463 74980611 1-s2.0-S187350612100310X-main.pdf 1-s2.0-S187350612100310X-main.pdf 1 656903901543B36D247D71EC6791B95E 74988c487ecbacb5c34312b2e16b62509ca39d6b61d83b0b2961ca46e59d60d2 0043bcdb-238c-11ed-92af-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=159369 https://www.sciencedirect.com/science/article/pii/S187350612100310X 0 af23e7f8-238b-11ed-92af-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=159368 Medicinska fakulteta 0 0 0