20.500.12556/RUL-138710 Invasive sinus aspergillosis with mycotic aneurysm of the vertebral artery and subarachnoid hemorrhage case report Invasive sinus aspergillosis is a rare life-threatening condition usually found in immunocompromised patients. The fungus spreads from paranasal sinuses into the central nervous system by direct extension or through blood vessels. Perineural spread is an uncommon mechanism of spread in invasive aspergillosis. A mycotic aneurysm is a dangerous complication of invasive sinus aspergillosis because of its insidious development and is often diagnosed only post-mortem after causing fatal intracranial hemorrhage. Intracranial vascular complications of invasive sinus aspergillosis require prompt recognition and treatment and should always be considered when a diagnosis of CNS aspergillosis is made. We present a case of invasive sinus aspergillosis in an apparently immunocompetent patient that manifested with a brain abscess, perineural spread of the infection, and mycotic aneurysm of the vertebral artery with subsequent rupture and fatal subarachnoid hemorrhage. This case highlights the possibility of perineural spread and hemorrhagic complications in invasive cerebral aspergillosis. aspergillosis sinusitis invasive sinus aspergillosis mycotic aneurysm perineural spread subarachnoid hemorrhage aspergiloza sinuzitis invazivna aspergiloza sinusov mikotična anevrizma subarahnoidna krvavitev true false true Angleški jezik Slovenski jezik Članek v reviji 2022-08-10 10:40:14 2022-08-10 10:40:15 2022-09-15 04:17:05 0000-00-00 00:00:00 2021 0 0 Str. 2651-2657 iss. 9 Vol. 16 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616 1930-0433 10.1016/j.radcr.2021.06.041 71115267 1-s2.0-S1930043321004192-main.pdf 1-s2.0-S1930043321004192-main.pdf 1 A5C23ECBC9C7D1FF6A7D75DE82F121FF 20d73355972d711ca713fc46d70b154793d78beebc862f2ecfefcb4cf86af811 b429f3b2-1889-11ed-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=159124 https://www.sciencedirect.com/science/article/pii/S1930043321004192 0 c4370639-1887-11ed-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=159123 Medicinska fakulteta 0 0 0