20.500.12556/RUL-137359 Differences in metal ions released from orthodontic appliances in an in vitro and in vivo setting The aim was to assess the composition of released metal ions from fixed orthodontic appliances both in an in vitro and in vivo setting and to compare their quantities to evaluate any possible health risks associated with them. For the in vitro setting, a set of 24 as-received sterile SS brackets, 2 SS sterile archwires, and 2 NiTi sterile archwires were aged for 90 days in artificial saliva, and released metal ion concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS), using matrix-matched standards for calibration. For the in vivo setting, 15 brackets, 15 SS, and 15 NiTi archwires were retrieved after 90 days of intraoral exposure in 15 subjects. Debris composition on each part of the orthodontic appliance was assessed using scanning electron microscopy with energy dispersive spectroscopy (SEM/EDS). The present study evidenced a difference in the composition of released metal ions from fixed orthodontic appliances detected in an in vitro and in vivo setting. Generally, the relative content of metal ions was higher in the retrieved debris than that released in artificial saliva. The concentration of released metal ions from all tested alloys was below the upper recommended limit of daily intake; however, possible local effects in terms of hypersensitivity due to their accumulation in the debris cannot be excluded even with such concentrations. orthodontic appliances fixed appliances biocompatible materials true false true Angleški jezik Ni določen Članek v reviji 2022-06-14 09:03:34 2022-06-14 09:03:35 2022-09-15 04:14:59 0000-00-00 00:00:00 2022 0 0 10 str. iss. 2, art. 190 Vol. 12 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 54 2079-6412 10.3390/coatings12020190 99817219 coatings-12-00190-v2.pdf coatings-12-00190-v2.pdf 1 731929A15E29B12A1456FA2DC359ADF1 87e3d3af78575b88be1557af09cdc44285acb21a7299a23fdfc8ad4ed753af09 4481b092-ebb0-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=157294 https://www.mdpi.com/2079-6412/12/2/190 0 046e784e-ebb0-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=157293 Zdravstvena fakulteta Medicinska fakulteta 0 0 0