20.500.12556/RUL-137345 Supercritical CO$_2$ plant extracts show antifungal activities against crop-borne fungi Fungal infections of cultivated food crops result in extensive losses of crops at the global level, while resistance to antifungal agents continues to grow. Supercritical fluid extraction using CO$_2$ (SFE-CO$_2$) has gained attention as an environmentally well-accepted extraction method, as CO$_2$ is a non-toxic, inert and available solvent, and the extracts obtained are, chemically, of greater or different complexities compared to those of conventional extracts. The SFE-CO$_2$ extracts of Achillea millefolium, Calendula officinalis, Chamomilla recutita, Helichrysum arenarium, Humulus lupulus, Taraxacum officinale, Juniperus communis, Hypericum perforatum, Nepeta cataria, Crataegus sp. and Sambucus nigra were studied in terms of their compositions and antifungal activities against the wheat- and buckwheat-borne fungi Alternaria alternata, Epicoccum nigrum, Botrytis cinerea, Fusarium oxysporum and Fusarium poae. The C. recutita and H. arenarium extracts were the most efficacious, and these inhibited the growth of most of the fungi by 80% to 100%. Among the fungal species, B. cinerea was the most susceptible to the treatments with the SFE-CO$_2$ extracts, while Fusarium spp. were the least. This study shows that some of these SFE-CO$_2$ extracts have promising potential for use as antifungal agents for selected crop-borne fungi. antifungal activity growth inhibition plant extract supercritical CO$_2$ extraction Botrytis cinerea Chamomilla recutita protiglivično delovanje zaviranje rasti rastlinski izvleček superkritična ekstrakcija CO$_2$ glive true false true Angleški jezik Slovenski jezik Članek v reviji 2022-06-13 13:08:03 2022-06-13 13:08:11 2022-09-15 04:14:58 0000-00-00 00:00:00 2022 0 0 15 str. iss. 3, art. 1132 Vol. 27 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 581.19:582.28 1420-3049 10.3390/molecules27031132 96933891 molecules-27-01132.pdf molecules-27-01132.pdf 1 164D63CA96A0F102B9629AB64FB7A667 a4a012785b3269e91c2fcc5b53f04744f6d6a8efa45dc7806eb5a1b9ff8d65b3 cc805cc3-eb09-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=157266 https://www.mdpi.com/1420-3049/27/3/1132 1 f17f69c0-eb08-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=157265 Fakulteta za farmacijo Biotehniška fakulteta 0 0 0