20.500.12556/RUL-137070 Phi 6 bacteriophage inactivation by metal salts, metal powders, and metal surfaces The interaction of phages with abiotic environmental surfaces is usually an understudied field of phage ecology. In this study, we investigated the virucidal potential of different metal salts, metal and ceramic powders doped with Ag and Cu ions, and newly fabricated ceramic and metal surfaces against Phi6 bacteriophage. The new materials were fabricated by spark plasma sintering (SPS) and/or selective laser melting (SLM) techniques and had different surface free energies and infiltration features. We show that inactivation of Phi6 in solutions with Ag and Cu ions can be as effective as inactivation by pH, temperature, or UV. Adding powder to Ag and Cu ion solutions decreased their virucidal effect. The newly fabricated ceramic and metal surfaces showed very good virucidal activity. In particular, 45%TiO$_2$ + 5%Ag + 45%ZrO$_2$ + 5%Cu, in addition to virus adhesion, showed virucidal and infiltration properties. The results indicate that more than 99.99% of viruses deposited on the new ceramic surface were inactivated or irreversibly attached to it. bacteriophage (phage) Phi6 metal salts ceramic–metal powders metals composite materials bakteriofagi Phi 6 kovinski ioni soli prah kompoziti true false true Angleški jezik Slovenski jezik Članek v reviji 2022-06-01 08:55:48 2022-06-01 08:55:49 2022-09-15 04:14:38 0000-00-00 00:00:00 2022 0 0 12 str. iss. 2, art. 204 Vol. 14 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 578.347:615.281.8:546.3 1999-4915 10.3390/v14020204 94779907 viruses-14-00204.pdf viruses-14-00204.pdf 1 4BFEF5152057AA5089DAA2FB5086FCDE e1e03ac3be1cd3493a0573a604a148c3fd101dccd3015e80c69c120462ca4a11 02dd8b45-e178-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=156936 https://www.mdpi.com/1999-4915/14/2/204 1 b9526c87-e177-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=156935 Biotehniška fakulteta Fakulteta za strojništvo 0 0 0