20.500.12556/RUL-136913 Diagnostic and therapeutic values of angiogenic factors in endometrial cancer Endometrial cancer (EC) is the most frequent gynecological malignancy in developed countries and requires a relatively invasive diagnostic evaluation and operative therapy as the primary therapeutic approach. Angiogenesis is one of the main processes needed for cancer growth and spread. The production of angiogenic factors (AFs) appears early in the process of carcinogenesis. The detection of AFs in plasma and tissue and a better understanding of the angiogenic properties of EC may contribute not only to earlier but also more specific diagnosis and consequently tailored and individual therapeutic approaches. AFs and their receptors also have high potential as binding sites for targeted cancer therapy. In this review, we discuss angiogenesis in EC and the characteristics of the AFs that most contribute to angiogenesis in EC. We also highlight therapeutic strategies that target angiogenesis as potential EC therapy. endometrial cancer angiogenesis biomarkers angiogenic factors anti-angiogenic therapy rak endometrija angiogeneza biomarkerji true false true Angleški jezik Slovenski jezik Članek v reviji 2022-05-24 15:03:12 2022-05-24 15:03:16 2022-09-15 04:14:25 0000-00-00 00:00:00 2022 0 0 14 str. iss. 1, art. 7 Vol. 12 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-006 2218-273X 10.3390/biom12010007 90507523 biomolecules-12-00007-v3.pdf biomolecules-12-00007-v3.pdf 1 728C3B3C59B60E858FD6436616B714FF 2617455dda2cbc03f2b4383322423d7d67c21fc5ede271e343f4d56530082824 0ce39877-db62-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=156722 https://www.mdpi.com/2218-273X/12/1/7 1 bf92e36c-db61-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=156721 Medicinska fakulteta 0 0 0