20.500.12556/RUL-136180 Biocatalytic process intensification via efficient biocatalyst immobilization, miniaturization, and process integration Despite their sustainability, the potential of biocatalytic processes in industrial production is far from being realized. The main challenges in this field are the development of highly active, robust, and stable biocatalysts, the efficient regeneration of cofactors, and the prevention of biocatalyst deactivation under harsh industrial conditions. In addition to biocatalyst engineering, efficient enzyme and cell immobilization plays a crucial role in process feasibility. Reactor miniaturization, continuous operation, and integration with in situ product removal, process analytics, and cascade reactions that reduce the number of process steps enable process intensification. Mathematical model–based reactor and process design comprising time-scale analysis and efficient capacity increase can push the boundaries of biocatalytic processes toward industrial requirements. This review highlights the latest trends in efficient biocatalyst immobilization, miniaturization, and process integration to intensify biocatalytic processes. microreactor continuous process biocatalyst immobilization reactor design process intensification mikroreaktorji kontinuirni procesi imobilizacija biokatalizatorjev načrtovanje reaktorjev intenzifikacija procesa true false true Angleški jezik Slovenski jezik Članek v reviji 2022-04-15 09:00:25 2022-04-15 09:00:26 2022-09-15 04:13:30 0000-00-00 00:00:00 2021 0 0 8 str. Vol. 32, art. 100546 Dec. 2021 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 0000-00-00 66.098 2452-2236 10.1016/j.cogsc.2021.100546 73824771 Biocatalytic_-_Polona_Plazl.pdf Biocatalytic_-_Polona_Plazl.pdf 1 BD9B43CCCA09A8CBF68407441F2C2111 42fb8de0db49106d174fa1030d5372b47f82a1bf9767976bb8d1a60cd2b1d59c d9473275-bc8a-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=155686 https://www.sciencedirect.com/science/article/pii/S2452223621001024 1 ab348008-bc89-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=155685 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0