20.500.12556/RUL-135509 Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental Croatian regions Lymphocytic choriomeningitis virus (LCMV) is a neglected human pathogen associated with aseptic meningitis, severe systemic infections in immunocompromised persons, and congenital anomalies. Data on the prevalence of LCMV infections are scarce. We analyzed the seroprevalence of LCMV in continental Croatian regions. A total of 338 serum samples of professionally exposed (forestry workers, hunters, agriculture workers in contact with rodents) and non-exposed populations (general population, pregnant women) were tested for the presence of LCMV antibodies using indirect immunofluorescence assay. No participants reported recent febrile disease. LCMV IgG antibodies were detected in 23/6.8% of participants: 9.8% exposed persons and 5.1% non-exposed persons (6.1% in the general population and 3.9% in pregnant women). No participants were LCMV IgM positive. Although higher seropositivity was found in males compared to females (8.9% vs. 4.7%), inhabitants of suburban/rural areas compared to inhabitants of urban areas (9.2% vs. 4.6%), and persons who used well as a source of water compared to those who used tap (11.4% vs. 5.6%), these differences did not reach statistical significance. Results of logistic regression showed that the presence of rodents in the house/yard and cleaning rodent nests were associated with an elevated risk for LCMV infection (OR = 2.962, 95% CI = 1.019–8.607). lymphocytic choriomeningitis virus seroprevalence general population professionally exposed pregnant women Croatia virus limfocitnega horiomeningitisa seroprevalenca splošno prebivalstvo true false true Angleški jezik Slovenski jezik Članek v reviji 2022-03-17 08:20:32 2022-03-17 08:20:33 2022-09-14 04:13:43 0000-00-00 00:00:00 2021 0 0 10 str. iss. 2, art. 67 Vol. 6 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.9 2414-6366 10.3390/tropicalmed6020067 67793923 RAZ_Vilibic-Cavlek_Tatjana_2021.pdf RAZ_Vilibic-Cavlek_Tatjana_2021.pdf 1 57EF1186485F31469854F27D299AEB8C ce7c626d1b9d1f2c4734e912ba4225d51871d5251f3e0fc74b0eb2a61ee1ca51 f7be11bf-a5c2-11ec-8556-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=154618 https://www.mdpi.com/2414-6366/6/2/67 1 ba294da7-a5c2-11ec-8556-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=154616 Medicinska fakulteta 0 0 0