20.500.12556/RUL-135421 Literaturni pregled in analiza podatkov o zdravilih za uravnavanje kislinsko-baznega ravnotežja v organizmu Literature review and data analysis of medications regualting acido-basic equilibrium in the body Kislinsko-bazno ravnotežje in vzdrževanje homeostaze v telesu je življenjskega pomena. Telesne tekočine imajo različne vrednosti pH, ki so uravnavane s pufri ter z izmenjevanjem kislin in baz preko ledvic, respiratornega sistema (pljuč) in jeter. V magistrski nalogi smo proučili vplive posameznih procesov na uravnavanje kislinsko-baznega ravnotežja. Proučili smo tudi vpliv bolezenskih stanj, starosti in zaužite hrane na to ravnotežje ter pregledali uporabo zdravil in neregistriranih pripravkov za vzdrževanje kislinsko-baznega ravnotežja in razkisanost telesa. Ugotovili smo, da je zmotno razmišljanje, da lahko z zaužito hrano vplivamo na pH krvi oziroma preprečujemo in zdravimo »zakisanost telesa«, pač pa s prehrano vplivamo na ravnotežje elektrolitov in pH seča. S starostjo se koncentracije posameznih ionov spreminjajo, metabolna acidoza je bolj izražena. Bolezenska stanja v telesu pogosto povzročijo motnje v kislinsko-baznem ravnotežju. Zdravila za uravnavanje kislinsko-baznega ravnotežja uravnavajo koncentracije elektrolitov. Na trgu so prisotni tudi neregistrirani izdelki za uravnavanje kislinsko-baznega ravnotežja, ki pa nimajo ustreznega želenega učinka na ravnotežje. Acido-basic equilibrium and maintenance of homeostasis is essential for life in the body. Body fluids have different pH values, which are regulated with buffers and with exchanging acid and base with kidney, respiratory system (lung) and liver. The effects of individual processes on the regulation of acido-basic equilibrium were studied in the master thesis. The impact of disease states, age and food intake on equilibrium were also studied and in addition, the use of medicines and unregistered preparations for acido-basic equilibrium maintenance and body deacidifying was reviewed. We have found that the diet does not influence the pH of the blood or prevent and treat »acidity of the body«. On the other hand, diet can affect electrolyte balance and the pH of urine. Concentrations of ions are changing with aging and metabolic acidosis is more pronounced. Diseases often disrupt the acido-basic equilibrium in the body. Medications for regulation of acido-basic equilibrium regulate electrolyte concentrations. We also found unregistered preparations meant for regulating acido-basic equilibrium on the market but in reality, they have no effect on the equilibrium. kislinsko-bazno ravnotežje homeostaza pH uravnavanje pH elektroliti acido-basic equilibrium homeostasis pH maintenance of pH electrolytes true false false Slovenski jezik Angleški jezik Magistrsko delo/naloga 2022-03-12 08:45:18 2022-03-12 08:45:23 2022-09-14 04:13:13 0000-00-00 00:00:00 2022 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1970-01-01 86859 7353.pdf 7353.pdf 1 19CE1D7033BBAF5138897102D074D1A7 bcacf644bde39e33cbdf9dc2be6cbb89ee8327d7cffd3e605bceee081044bcc9 5f92f7b6-a1d8-11ec-8556-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=154485 Fakulteta za farmacijo 0 0 0