20.500.12556/RUL-135347 Hemodynamic response to high- and low-load resistance exercise in patients with coronary artery disease a randomized, crossover clinical trial Low-load resistance exercise (LL-RE) is recommended as an adjunct therapy to aerobic exercise during cardiac rehabilitation in patients with coronary artery disease. The safety and hemodynamic response to high-load (HL) RE remain unknown. The aim of this study was to evaluate the hemodynamic response during both HL-RE and LL-RE prior to cardiac rehabilitation. Forty-three patients with coronary artery disease and/or percutaneous coronary intervention performed three sets of leg-press exercise using HL-RE (eight repetitions at the intensity of 80% of one repetition maximum (1-RM)) and LL-RE (16 repetitions at the intensity of 40% 1-RM) in a randomized crossover sequence. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and rating of perceived exertion were measured at baseline, after each set of RE and post-exercise. No clinically relevant changes in HR and BP or in patient-reported symptoms were recorded during HL-RE or LL-RE. Compared with baseline, HR and SBP increased during LL-RE (from 66 bpm to 86 bpm, time effect: p < 0.001; from 129 mmHg to 146 mmHg, time effect: p < 0.001) and HL-RE (from 68 bpm to 86 bpm, time effect: p < 0.001; from 130 mmHg to 146 mmHg, time effect: p < 0.001). Compared with HL-RE, the increase in HR was greater after the final set of LL-RE (32% vs. 28%, p = 0.015), without significant differences in SBP and DBP between LL-RE and HL-RE. Rating of perceived exertion was higher after the 1st set of HL-RE compared with LL-RE (median (interquartile range): 6 (5–7) vs. 6 (5–6), p = 0.010). In patients with coronary artery disease, both HL-RE and LL-RE were safe and well-tolerated. Hemodynamic changes were similar and within the physiological response to RE. sport cardiac rehabilitation resistance training blood pressure heart rate šport srčno-žilna rehabilitacija vztrajnostni trening krvni tlak srčni utrip true false true Angleški jezik Slovenski jezik Članek v reviji 2022-03-08 14:29:12 2022-03-08 14:29:15 2022-09-14 04:12:55 0000-00-00 00:00:00 2021 0 0 12 str. iss. 8, art. 3905 Vol. 18 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.1:796.01 1660-4601 10.3390/ijerph18083905 59012611 RAZ_Kambic_Tim_2021.pdf RAZ_Kambic_Tim_2021.pdf 1 5FA98ED63FED75FC6E7FD3B4F452FBA1 d88050bab94ee8bdf0477dbc47349508c15eecc0a7bc95a69cd44782b8ab3c3f c23ca03c-9ee3-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=154376 https://www.mdpi.com/1660-4601/18/8/3905 1 7a040a22-9ee3-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=154375 Fakulteta za šport Medicinska fakulteta 0 0 0