20.500.12556/RUL-135028 Genomic characterization of the three Balkan livestock guardian dogs Balkan Livestock Guardian Dogs (LGD) were bred to help protect sheep flocks in sparsely populated, remote mountainous areas in the Balkans. The aim of this study was genomic characterization (107,403 autosomal SNPs) of the three LGD breeds from the Balkans (Karst Shepherd, Sharplanina Dog, and Tornjak). Our analyses were performed on 44 dogs representing three Balkan LGD breeds, as well as on 79 publicly available genotypes representing eight other LGD breeds, 70 individuals representing seven popular breeds, and 18 gray wolves. The results of multivariate, phylogenetic, clustering (STRUCTURE), and FST differentiation analyses showed that the three Balkan LGD breeds are genetically distinct populations. While the Sharplanina Dog and Tornjak are closely related to other LGD breeds, the Karst Shepherd is a slightly genetically distinct population with estimated influence from German Shepard (Treemix analysis). Estimated genomic diversity was high with low inbreeding in Sharplanina Dog (Ho = 0.315, He = 0.315, and FROH>2Mb = 0.020) and Tornjak (Ho = 0.301, He = 0.301, and FROH>2Mb = 0.033) breeds. Low diversity and high inbreeding were estimated in Karst Shepherds (Ho = 0.241, He = 0.222, and FROH>2Mb = 0.087), indicating the need for proper diversity management. The obtained results will help in the conservation management of Balkan LGD dogs as an essential part of the specific grazing biocultural system and its sustainable maintenance. canine livestock guardian dogs conservation management genomic diversity and characterization pastirski psi balkanske pasme genetika genomika true false true Angleški jezik Slovenski jezik Članek v reviji 2022-02-17 16:44:21 2022-02-17 16:44:21 2022-09-14 04:11:16 0000-00-00 00:00:00 2021 0 0 16 str. iss. 4, art. 2289 Vol. 13 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.7:574 2071-1050 10.3390/su13042289 52551427 RAZ_Janes_Mateja_2021.pdf RAZ_Janes_Mateja_2021.pdf 1 169F87FD048A9CEFBAF0FF9FA1FE322B 065e874e166d380d7c931496b1fb7f2feafadf7449d6881408f428dc4157b600 79c9a6d6-9008-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=153859 https://www.mdpi.com/2071-1050/13/4/2289 1 3c20d76b-9008-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=153858 Biotehniška fakulteta 0 0 0