20.500.12556/RUL-134377 Course and outcome of erythema migrans in pregnant women Information on Lyme borreliosis (LB) during pregnancy is limited. In the present study, the course and outcome of erythema migrans (EM) in 304 pregnant women, diagnosed in the period 1990-2015, was assessed and compared with that in age-matched non-pregnant women. The frequency of unfavorable outcome of pregnancies was also evaluated. The pregnant women reported constitutional symptoms less frequently than the non-pregnant women (22.4% vs. 37.2%, p < 0.001). Pregnant women diagnosed with EM later during pregnancy had a lower probability of reporting constitutional symptoms (odds ratio = 0.97 for 1-week difference in gestation week at diagnosis of EM, 95% CI: 0.94-0.99, p = 0.02). The outcome of pregnancy was unfavorable in 42/304 (13.8%) patients: preterm birth in 22/42 (52.4%), fetal/perinatal death in 10/42 (23.8%), and/or anomalies in 15/42 (35.7%). Several patients had potential explanation(s) for the unfavorable outcome. In conclusion, the course of early LB during pregnancy is milder than in age-matched non-pregnant women. The outcome of pregnancy with the treatment approach used in the present study (i.v. ceftriaxone 2 g once daily for 14 days) is favorable. erythema migrans Lyme borreliosis gestation pregnancy outcome Borrelia burgdorferi sensu lato eritema migrans lymska borelioza gestacija true false true Angleški jezik Slovenski jezik Članek v reviji 2022-01-12 09:59:27 2022-01-12 09:59:32 2022-09-13 03:54:48 0000-00-00 00:00:00 2020 0 0 18 str. iss. 8, art. 2364 Vol. 9 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.9 2077-0383 10.3390/jcm9082364 23543811 RAZ_Maraspin-Carman_Vera_2020.pdf RAZ_Maraspin-Carman_Vera_2020.pdf 1 9BF56C17EA3E60B7324B7960D118059C 1f433b1a380dfd5a45a07714bed36a5719cd885adc726c1dd946db006941edb4 9d572925-7386-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=152793 https://www.mdpi.com/2077-0383/9/8/2364 1 c77b0798-7385-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=152792 Medicinska fakulteta 0 0 0