20.500.12556/RUL-134067 Hanseniaspora smithiae sp. nov., a novel apiculate yeast species from Patagonian Forests that lacks the typical genomic domestication signatures for fermentative environments During a survey of Nothofagus trees and their parasitic fungi in Andean Patagonia (Argentina), genetically distinct strains of Hanseniaspora were obtained from the sugar-containing stromata of parasitic Cyttaria spp. Phylogenetic analyses based on the single-gene sequences (encoding rRNA and actin) or on conserved, single-copy, orthologous genes from genome sequence assemblies revealed that these strains represent a new species closely related to Hanseniaspora valbyensis. Additionally, delimitation of this novel species was supported by genetic distance calculations using overall genome relatedness indices (OGRI) between the novel taxon and its closest relatives. To better understand the mode of speciation in Hanseniaspora, we examined genes that were retained or lost in the novel species in comparison to its closest relatives. These analyses show that, during diversification, this novel species and its closest relatives, H. valbyensis and Hanseniaspora jakobsenii, lost mitochondrial and other genes involved in the generation of precursor metabolites and energy, which could explain their slower growth and higher ethanol yields under aerobic conditions. Similarly, Hanseniaspora mollemarum lost the ability to sporulate, along with genes that are involved in meiosis and mating. Based on these findings, a formal description of the novel yeast species Hanseniaspora smithiae sp. nov. is proposed, with CRUB 1602$^H$ as the holotype. apiculate yeast new species phylogenomics OGRI gene loss speciation domestication kvasovke Hanseniaspora taksonomija true false true Angleški jezik Slovenski jezik Članek v reviji 2021-12-23 10:39:00 2021-12-23 10:39:00 2023-03-28 10:57:32 0000-00-00 00:00:00 2021 0 0 11 str. art. 679894 Vol. 12 Jul. 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 579.8:582.282.23 1664-302X 10.3389/fmicb.2021.679894 72059139 RAZ_Cadez_Neza_2021.pdf RAZ_Cadez_Neza_2021.pdf 1 EC5404F1B66E1E2BA8289879A10FA046 28099f4e77a5fcd1ebde6721f7555dab5f16ce3c311bd9b847460d4e54b0ace2 43675745-63d7-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=152371 https://www.frontiersin.org/articles/10.3389/fmicb.2021.679894/full 1 04ec1d22-63d4-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=152368 Biotehniška fakulteta 0 0 0