20.500.12556/RUL-133377 A preliminary study of the virome of the South American free-tailed bats (Tadarida brasiliensis) and identification of two novel mammalian viruses Bats provide important ecosystem services as pollinators, seed dispersers, and/or insect controllers, but they have also been found harboring different viruses with zoonotic potential. Virome studies in bats distributed in Asia, Africa, Europe, and North America have increased dramatically over the past decade, whereas information on viruses infecting South American species is scarce. We explored the virome of Tadarida brasiliensis, an insectivorous New World bat species inhabiting a maternity colony in Rosario (Argentina), by a metagenomic approach. The analysis of five pooled oral/anal swab samples indicated the presence of 43 different taxonomic viral families infecting a wide range of hosts. By conventional nucleic acid detection techniques and/or bioinformatics approaches, the genomes of two novel viruses were completely covered clustering into the Papillomaviridae (Tadarida brasiliensis papillomavirus type 1, TbraPV1) and Genomoviridae (Tadarida brasiliensis gemykibivirus 1, TbGkyV1) families. TbraPV1 is the first papillomavirus type identified in this host and the prototype of a novel genus. TbGkyV1 is the first genomovirus reported in New World bats and constitutes a new species within the genus Gemykibivirus. Our findings extend the knowledge about oral/anal viromes of a South American bat species and contribute to understand the evolution and genetic diversity of the novel characterized viruses. Tadarida brasiliensis metagenomics bats Papillomaviridae TbraPV1 Genomoviridae TbGkyV1 Tadarida brasiliensis metagenomika netopirji true false true Angleški jezik Slovenski jezik Članek v reviji 2021-11-24 13:51:24 2021-11-24 13:51:31 2023-06-09 14:04:46 0000-00-00 00:00:00 2020 0 0 23 str. iss. 4, art. 422 Vol. 12 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.9 1999-4915 10.3390/v12040422 34773209 RAZ_Bolatti_Elisa_2020.pdf RAZ_Bolatti_Elisa_2020.pdf 1 FD82B3B335E2518853EA1F3E2FD809EE f945abc7cd320cf87032cad3ed5ab62bbce66155b06fa4560ef36b225c90ff95 59fd3023-4d25-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=151398 https://www.mdpi.com/1999-4915/12/4/422 1 2ad62171-4d25-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=151397 Medicinska fakulteta 0 0 0