20.500.12556/RUL-132827 Uric acid and plant-based nutrition Plant-based diets (PBDs) are associated with decreased risk of morbidity and mortality associated with important noncommunicable chronic diseases. Similar to animal-based food sources (e.g., meat, fish, and animal visceral organs), some plant-based food sources (e.g., certain soy legume products, sea vegetables, and brassica vegetables) also contain a high purine load. Suboptimally designed PBDs might consequently be associated with increased uric acid levels and gout development. Here, we review the available data on this topic, with a great majority of studies showing reduced risk of hyperuricemia and gout with vegetarian (especially lacto-vegetarian) PBDs. Additionally, type of ingested purines, fiber, vitamin C, and certain lifestyle factors work in concordance to reduce uric acid generation in PBDs. Recent limited data show that even with an exclusive PBD, uric acid concentrations remain in the normal range in short- and long-term dieters. The reasonable consumption of plant foods with a higher purine content as a part of PBDs may therefore be safely tolerated in normouricemic individuals, but additional data is needed in hyperuricemic individuals, especially those with chronic kidney disease. uric acid plant-based diets chronic diseases purine hyperuricemia gout true false true Angleški jezik Ni določen Članek v reviji 2021-11-04 09:36:52 2021-11-04 09:36:53 2022-09-12 04:13:54 0000-00-00 00:00:00 2019 0 0 15 str. iss. 8, art. 1736 Vol. 11 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.6 2072-6643 10.3390/nu11081736 6381484 RAZ_Jakse_Bostjan_2019.pdf RAZ_Jakse_Bostjan_2019.pdf 1 3CE1A2DAE7E66A1F34675A71307DD7B5 84561ae77f79d8da7a788aa6a54930074676e26617d78de17a8538800f54a9a1 d673809b-3d4a-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=150543 https://www.mdpi.com/2072-6643/11/8/1736 1 50f8a51e-3d4a-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=150542 Biotehniška fakulteta Fakulteta za šport 0 0 0