20.500.12556/RUL-132560 Analyzing the photoprotection efficiency of sunscreens containing antioxidants under disinfection conditions Sunscreens ensure thorough protection against sunburn. The delivery of UV filters into the stratum corneum and viable epidermis could be reduced by the use of antioxidants (such as β-carotene and trans-resveratrol, alone or combined). The presence/absence of antioxidants (trans-resveratrol and β-carotene) in formulations containing benzophenone-3 (UV-filter) and their efficiency under disinfection and neutral conditions are studied and compared. The trial was conducted on 38 people. The prepared ointments were applied to the participants’ forearms, irradiated and monitored by reflectance colorimetry after 0, 4, 6, and 8 min. Descriptive statistics were used to describe the skin color’s main characteristics and the F-ratio was used to test overall differences. The ointments containing antioxidants and benzophenone-3 were the most efficient, followed by those with benzophenone-3 alone. It was proven that photoprotection with benzophenone-3 is still effective, despite the formation of its chlorinated products. Due to the short time of exposure to disinfecting conditions, it could be assumed that benzophenone-3 was only partially chlorinated. This clinical study demonstrated that formulations containing antioxidants are likely to be more suitable for protecting skin against UVB irradiation than a UV filter alone. ultraviolet radiation UV filter benzophenone-3 trans-resveratrol ß-carotene chlorinated products ultravijolično sevanje UV filter benzofenon-3 trans-resveratrol ß-karoten klorirani izdelki true false true Angleški jezik Slovenski jezik Članek v reviji 2021-10-29 09:20:21 2021-10-29 09:20:21 2022-09-12 04:12:51 0000-00-00 00:00:00 2021 0 0 11 str. iss. 11, art. 1720 Vol. 10 2021 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 0000-00-00 544.526:614.898:613.165 2076-3921 10.3390/antiox10111720 82825731 antioxidants-10-01720.pdf antioxidants-10-01720.pdf 1 C54A927F53A9CAF3FB7EEEBC24D3DB49 126f3edf586ec3530ad2f58467adf562dccbf68066e3a85d2913522d30429ccf e5263566-cc75-11ec-8aca-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=156140 https://www.mdpi.com/2076-3921/10/11/1720 1 a459a897-3888-11ec-abdb-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=150227 Zdravstvena fakulteta Biotehniška fakulteta 0 0 0