20.500.12556/RUL-131076 Erythropoietin and its angiogenic activity Erythropoietin (EPO) is the main hematopoietic hormone acting on progenitor red blood cells via stimulation of cell growth, differentiation, and anti-apoptosis. However, its receptor (EPOR) is also expressed in various non-hematopoietic tissues, including endothelium. EPO is a pleiotropic growth factor that exhibits growth stimulation and cell/tissue protection on numerous cells and tissues. In this article we review the angiogenesis potential of EPO on endothelial cells in heart, brain, and leg ischemia, as well as its role in retinopathy protection and tumor promotion. Furthermore, the effect of EPO on bone marrow and adipose tissue is also discussed. erythropoietin erythropoietin receptor cancer endothelial angiogenesis eritropoetin receptor eritropoetina rak true false true Angleški jezik Slovenski jezik Članek v reviji 2021-09-22 10:36:05 2021-09-22 10:36:06 2022-09-10 04:09:47 0000-00-00 00:00:00 2017 0 0 14 str. iss. 7, art. 1519 Vol. 18 Jul. 2017 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-006 1422-0067 10.3390/ijms18071519 33325785 RAZ_Kimakova_Patricia_2017.pdf RAZ_Kimakova_Patricia_2017.pdf 1 7D3672B9EF8E9899CD14524C747E0C64 c8f7734b1125d40b7d4fe6fee12f5f86e0386cae1ec22b2a064d90542d2c8a2a 22bbddb6-1b80-11ec-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=148322 http://www.mdpi.com/1422-0067/18/7/1519 1 dc4a3016-1b7f-11ec-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=148321 Medicinska fakulteta 0 0 0