20.500.12556/RUL-128573 Hyperspectral evaluation of peritoneal fibrosis in mouse models Analysis of morphological changes of the peritoneal membrane is an essential part of animal studies when investigating molecular mechanisms involved in the development of peritoneal fibrosis or testing the effects of potential therapeutic agents. Current methods, such as histology and immunohistochemistry, require time consuming sample processing and analysis and result in limited spatial information. In this paper we present a new method to evaluate structural and chemical changes in an animal model of peritoneal fibrosis that is based on hyperspectral imaging and a model of light transport. The method is able to distinguish between healthy and diseased subjects based on morphological as well as physiological parameters such as blood and scattering parameters. Furthermore, it enables evaluation of changes, such as degree of inflammation and fibrosis, that are closely related to histological findings. medical physics medical imaging medicinska fizika medicinsko slikanje true false true Angleški jezik Slovenski jezik V članku navedeno: "© 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement"; s povezavo https://www.osapublishing.org/library/license_v1.cfm. (20. 7. 2021) Članek v reviji 2021-07-20 12:41:00 2021-07-20 12:41:00 2023-05-30 03:27:12 0000-00-00 00:00:00 2020 0 0 Str. 1991-2006 no. 4, art. 387837 Vol. 11 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-073 2156-7085 10.1364/BOE.387837 3414372 RAZ_Stergar_Jost_2020.pdf RAZ_Stergar_Jost_2020.pdf 1 6D7D50B42FA99758070E6C8D84885E8F 3dcb6f127cb417a4c4ef12a6faa397c328e6ce1a655257f32dd86761ee2eb592 12fe712e-e947-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=145360 https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-11-4-1991&id=429048 0 02ace67e-e947-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=145359 Fakulteta za matematiko in fiziko Medicinska fakulteta 0 0 0