20.500.12556/RUL-122071 Electroporation-based treatments in small animal veterinary oral and maxillofacial oncology Electroporation is a method of inducing an increase in permeability of the cell membrane through the application of an electric field and can be used as a delivery method for introducing molecules of interest (e.g., chemotherapeutics or plasmid DNA) into cells. Electroporation-based treatments (i.e., electrochemotherapy, gene electrotransfer, and their combinations) have been shown to be safe and effective in veterinary oncology, but they are currently mostly recommended for the treatment of those solid tumors for which clients have declined surgery and/or radiotherapy. Published data show that electroporation-based treatments are also safe, simple, fast and cost-effective treatment alternatives for selected oral and maxillofacial tumors, especially small squamous cell carcinoma and malignant melanoma tumors not involving the bone in dogs. In these patients, a good local response to treatment is expected to result in increased survival time with good quality of life. Despite emerging evidence of the clinical efficacy of electroporation-based treatments for oral and maxillofacial tumors, further investigation is needed to optimize treatment protocols, improve clinical data reporting and better understand the mechanisms of patients' response to the treatment. electroporation electrochemotherapy ECT gene electrotransfer oral tumors dogs cats mouth neoplasms elektroporacija elektrokemoterapija genski elektroprenos ustni tumorji psi mačke true false true Angleški jezik Slovenski jezik Članek v reviji 2020-11-19 13:55:14 2020-11-19 13:55:19 2025-04-23 09:57:18 0000-00-00 00:00:00 2020 0 0 17 str. Vol. 7, art. 575911 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 636.09:616 2297-1769 10.3389/fvets.2020.575911 30212611 3969402 fvets-07-575911_(1).pdf fvets-07-575911_(1).pdf 1 0EC61E344C24B88D918E43300FE0CD79 d0e7b0d87e8e1d4df9310945c3a2a48c3c93c0a8f1b2d48c8908470ad43b0418 fc7e213a-1b6d-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=208649 https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2020.575911/full 0 0a808847-1f82-11f0-b232-0050569b8976 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=209650 Veterinarska fakulteta 0 0 0