20.500.12556/RUL-119690 Načini zamreževanja TEMPO modificirane nanoceluloze za uporabo v dostavnih sistemih zdravil Crosslinking methods of TEMPO modified nanocellulose used in drug delivery Nanoceluloza je material na osnovi celuloze, ki ima vsaj eno zmed svojih zunanjih dimenzij v nano območju. S svojo nizko težo, veliko trdnostjo in biokompatibilnostjo je v zadnjem času postala izredno zanimiva na številnih področjih. Uporablja se kot osnova v hidrogelih, ki se v farmacevtski industriji uporabljajo za tarčno in kontrolirano sproščanje učinkovin v telesu ter njihovo dostavo. Hidrogeli so v splošnem tridimenzionalna polimerna omrežja, ki lahko absorbirajo in zadržijo velike količine vode. Raziskovalci poskušajo lastnosti hidrogelov izboljšati z zamreževanjem. Ločimo fizikalno in kemijsko zamreženje. Fizikalno zamreženi hidrogeli nastanejo z medmolekulskimi reverzbilnimi interakcijami, medtem ko kemijsko zamreženi hidrogeli nastanejo preko kovalentnih vezi. Nanocellulose is a cellulose-based material that has at least one of its external dimensions in the nano range. With its low weight, high strength and biocompatibility, it has recently become extremely interesting in many areas. It is used as a base in hydrogels, which are used in the pharmaceutical industry for targeted and controlled release of active substances in the body and their delivery. Hydrogels are generally three-dimensional polymer networks that can absorb and retain large amounts of water. Scientists are trying to improve the properties of hydrogels by crosslinking. We distinguish between physical and chemical crosslinking. Physically crosslinked hydrogels are formed by intramolecular reversible interactions, while chemically crosslinked hydrogels are formed through covalent bonds. nanoceluloza hidrogeli zamreževanje transportni sistemi zdravil nanocellulose hydrogels crosslinking drug delivery systems true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2020-09-10 16:25:00 2020-09-10 16:25:04 2022-08-31 03:54:17 0000-00-00 00:00:00 2020 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 11101 31476739 Oman_Klemen_-_Nacini_zamrezevanja_TEMPO_modificirane_nanoceluloze_za_uporabo_v_dostavnih_sistemi.pdf Oman_Klemen_-_Nacini_zamrezevanja_TEMPO_modificirane_nanoceluloze_za_uporabo_v_dostavnih_sistemi.pdf 1 6BFFE92FAD2583FDF778AE06C61F8B04 d218a0d8ffdb21bf790619ee4381ef8b07eb1fe56afd69520139c25c14e2e479 e5341bce-a1b9-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=134415 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0