20.500.12556/RUL-119402 Sinteza nekaterih halkogeniranih derivatov Synthesis of some chalcogenated derivatives Halkogeni derivati so pomembne spojine. V organski kemiji lahko služijo kot intermediati v sintezi, mnoge halkogene spojine pa imajo tudi biološko delovanje. V zadnjih letih se je organska kemija selena in telurja zelo razvila. Selenov atom je lahko v organoselenove spojine vključen kot elektrofil ali nukleofil. Poznamo elektrofilne kot tudi nukleofilne selenove reagente. V diplomskem delu bom opisala nekatere metode s katerimi jih lahko sintetiziramo. Selenocianate lahko pripravimo z direktnim ali indirektnim seleniliranjem. V kemiji so uporabni kot intermediati za nadaljnje sinteze. Zaradi svojih različnih bioloških lastnosti pa se lahko uporabljajo tudi v kemoterapiji. Tako kot organoselenova, ima tudi organotelurjeva kemija široko področje za nadaljnji razvoj. Tako npr. selen in telur vsebujejo 5-arilhalkogenoalkil-1H-tetrazoli, ki imajo protiglivično delovanje. Chalcogen derivatives are important compounds. In organic chemistry they can serve as intermediates in synthesis, and many of chalcogen compounds also exhibit biological activity. In recent years, chemistry using selenium and tellurium has evolved greatly. Selenium atom can be incorporated into compounds as a nucleophile or an electrophile. Electrophilic as well as nucleophilic selenium reagents are known. In this thesis I will describe some methods by which we can synthesise them. Selenocyanates can be prepared by direct or indirect selenocyanation. In chemistry they can be used as intermediates for further synthesis. Due to their various biological properties, they can also be used in chemotherapy. Like organoselenes, organotellurium chemistry has a wide field with greater possibilities for development. For example, selenium and tellurium containing 5-arylchalcogenoalkyl-1H-tetrazoles have displayed anifungal activity. organoselenove spojine organotelurjeve spojine halkogeni elementi organoselenium compounds organotellurium compounds chalcogen elements true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2020-09-08 12:20:08 2020-09-08 12:20:11 2022-08-31 03:52:56 0000-00-00 00:00:00 2020 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 10082 28691715 Suklje_Natasa_-_Sinteza_nekaterih_halkogeniranih_derivatov.pdf Suklje_Natasa_-_Sinteza_nekaterih_halkogeniranih_derivatov.pdf 1 8BBE603BB11B6044FF65A3C14E93DDFE f3fb40d1d5f561aeb774ae32ef83859e244b67a4ef50b1e48012710b23afba73 d1819111-a1b9-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=134113 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0