20.500.12556/RUL-118114 Derivati oksindola in isatina ter njihova uporaba v organokataliziranih pretvorbah – sinteza izotiocianatov na osnovi 5-fluoroindolin-2,3-diona Oxindole and isatin derivatives and their application in organocatalyzed transformations – synthesis of 5-fluoroindoline -2,3-dione derived isothiocyanates V diplomskem delu sem predstavil organokatalizo, na kratko preletel nekaj pomembnejših odkritij na področju organokatalize ter opisal nekaj bolj razširjenih metod organokatalize. Kot izhodne spojine v organokatalizi sem predstavil oksindol, isatin in njune derivate ter sintezo le-teh. Sinteza derivatov oksindola ter isatina je v današnjem času privlačna predvsem zaradi njihove biološke aktivnosti. Mnogi derivati se prav zaradi tega lahko uporabljajo kot učinkovine v zdravilih. Podrobneje sem predstavil tudi sintezo izotiocianata na osnovi 5-fluoroindolin-2,3-diona. This work explores organocatalysis, some of the more significant advances in organocatalysis throughout history and methods most commonly used in various organocatalytic reactions. The use of oxindole, isatin and their derivatives as starting compounds in the field of organocatalysis is very prevalent because of their bioactivity. Furthermore, many derivatives are, for the reasons listed, used as pharmaceuticals in various drugs. In addition, the synthesis of 5-fluoroindoline-2,3-dione derived isothiocyanates are presented in more detail. Organokataliza oksindol isatin izotiocianat Organocatalysis oxindole isatin isothiocyanate true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2020-08-20 15:05:00 2020-08-20 15:05:05 2022-08-30 04:01:38 0000-00-00 00:00:00 2020 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 11181 26507267 Vesel_Ziga_-_Derivati_oksindola_in_isatina_ter_njihova_uporaba_v_organokataliziranih_pretvorbah_.pdf Vesel_Ziga_-_Derivati_oksindola_in_isatina_ter_njihova_uporaba_v_organokataliziranih_pretvorbah_.pdf 1 AE64F74D6A64486FD779EBD25C12E09E 6f907852607ab8ed88631f403112ea47a85fc3e2d760fc2dd9d8e4ca8113d4e9 510f2410-a1b9-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=132105 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0