20.500.12556/RUL-116799
Validacija HPLC metode za selektivno določevanje kanabinoidov
Validation of the HPLC method for selective determination of cannabinoids
Kanabinoidi oziroma fitokanabinoidi so organske aromatske molekule, ki jih najdemo na rastlini Konoplja. Za človeško farmakologijo so te molekule zanimive, saj se nanje odzivajo endokanabinoidni receptorji v telesu. Človeško telo namreč proizvaja telesu lastne endokanabinoide. Vedno bolj se jim pripisuje pozitivne, blagodejne in celo zdravilne učinke na človeško telo. V ta namen se je razvila in se še razvija potreba po analitskih tehnikah, ki dajejo verodostojne in točne rezultate
V sklopu diplomskega dela smo preverili in validirali eno izmed analitskih tehnik določevanja kanabinoidov po International Council of Harmonisation (ICH) smernicah. High Performance Liquid Chromatography (HPLC) metoda za selektivno določanje kanabinoidov nam omogoča identifikacijo in kvantifikacijo kanabinoidov v številnih vzorcih, ki so ključni pri razvoju in raziskavah ter vplivih fitokanabinoidov na človeško telo.
Cannabinoids or Phytocannabinoids are organic aromatic molecules found in the Cannabis plant. These organic molecules are interesting for human pharmacology not only as the receptors response to them but also because our body is able to produce endocannabinoids of its own. They have been credited with having positive, beneficial and even healing effects. As the result of these properties, the need for analytical techniques that produce credible and accurate results has developed.
This thesis examines one of the analytical techniques for determinating cannabinoids according to International Council of Harmonisation guidelines (ICH). The High Performance Liquid Chromatography method (HPLC) for the selective determination of cannabinoids enables us to identify and authentically quantify them in a number of different samples. Having a good analytical techinque is crucial in research, development and monitoring the effects of phytocannabinoids on the human body.
High Performance Liquid Chromatography (HPLC) kromatografija
International Council of Harmonisation (ICH)
Validacija metode
Fitokanabinoidi
High Performance Liquid Chromatography (HPLC) kromatografija Chromatography
International Council of Harmonisation (ICH)
Method validation
Phytocannabinoids
true
false
false
Slovenski jezik
Angleški jezik
Diplomsko delo/naloga
2020-06-11 11:15:01
2020-06-11 11:15:08
2022-08-29 03:39:11
0000-00-00 00:00:00
2020
0
0
0000-00-00
NiDoloceno
NiDoloceno
NiDoloceno
0000-00-00
0000-00-00
0000-00-00
12441
19588099
Stefancic_Matevz_-_Validacija_HPLC_metode_za_selektivno_dolocevanje_kanabinoidov.pdf
Stefancic_Matevz_-_Validacija_HPLC_metode_za_selektivno_dolocevanje_kanabinoidov.pdf
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https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=130487
Fakulteta za kemijo in kemijsko tehnologijo
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