20.500.12556/RUL-114905 Soft nanotechnology the potential of polyelectrolyte multilayers against E. coli adhesion to surfaces Mehka nanotehnologija anti-adhezivni potencial polielektrolitskih premazov proti adheziji E. coli na površine Preventing bacterial attachment to surfaces is the most efficient approach to controlling biofilm proliferation. The aim of this study was to compare anti-adhesion potentials of 5 and 50 mmol/L polyelectrolyte multilayers of poly(allylamine hydrochloride)/poly(sodium 4–styrenesulfonate), poly(4-vinyl-N-ethylpyridinium bromide)/ poly(sodium 4–styrenesulfonate), and poly(4-vinyl-N-isobutylpyridinium bromide)/poly(sodium 4–styrenesulfonate) against Escherichia coli. Glass surface was covered with five polyelectrolyte layers and exposed to bacterial suspensions. Poly(4-vinyl-N-ethylpyridinium bromide)/poly(sodium 4–styrenesulfonate) was the most effective against bacterial adhesion, having reduced it by 60 %, followed by poly(4-vinyl-N-isobutylpyridinium bromide)/poly(sodium 4– styrenesulfonate) (47 %), and poly(allylamine hydrochloride)/poly(sodium 4–styrenesulfonate) (38 %). Polyelectrolyte multilayers with quaternary amine groups have a significant anti-adhesion potential and could find their place in coatings for food, pharmaceutical, and medical industry. Preprečevanje adhezije bakterij na površine je najbolj učinkovit način obvladovanja rasti biofilmov. Namen te raziskave je bil analizirati anti-adhezivni potencial 5 in 50 mmol/L polielektrolitskih plasti poli(alilamin hidroklorid)/poli(natrijev 4-stirensulfonat), poli(4-vinil-N-etilpiridin bromid/ poli(natrijev 4-stirensulfonat) in poli(4-vinil-N-izobutilpiridin bromid/poli(natrijev 4-stirensulfonat) na bakterijo E. coli. Pet zaporednih plasti polielektrolitov je bilo sestavljenih na steklenih površinah in izpostavljenih bakterijski suspenziji. Rezultati kažejo, da 50 mmol/L poli(4-vinil-N-etilpiridin bromid/poli(natrijev 4-stirensulfonat) najbolj učinkovito prepreči adhezijo bakterij 0,4 log bakt./mm2 (60 %), sledi mu poli(4-vinil-N-izobutilpiridin bromid/ poli(natrijev 4-stirensulfonat) 0,3 log bakt. mm-2 (47 %) in poli(alilamin hidroklorid)/poli(natrijev 4-stirensulfonat) 0,2 log bakt. mm-2 (38 %). Ta raziskava dokazuje, da polieletrolitske plasti z kvartarneamino skupinami igrajo pomembno vlogo pri preprečevanju adhezije bakterij in zato predstavljajo pomembno uporabo v živilski in farmacevtski industriji ter v medicini. anti-adhesion potentials bacterial adhesion E. coli surface hygiene polyelectrolyte multilayers anti-adhezivni potencial bakterijska adhezija E. coli higiena površin polielektrolitske plasti true false true Angleški jezik Slovenski jezik Neznano 2020-03-30 13:08:36 2020-03-30 13:08:36 2022-08-27 03:58:32 0000-00-00 00:00:00 2020 0 0 Str. 63-68 no. 1 Vol. 71 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 614:579.2 0004-1254 10.2478/aiht-2020-71-3319 5789291 3833858 RAZ_Fink_Rok_2020.pdf RAZ_Fink_Rok_2020.pdf 1 B6504EC8C31385D5AC919105EC92A0D9 904f87308c5d295fae8d64eeee4a1a62d348d85411bac9701c2862afdff3f6db 4c31366f-a1b8-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=127282 Zdravstvena fakulteta 0 0 0