20.500.12556/RUL-114125 Global phylogeographic and admixture patterns in Grey wolves and genetic legacy of an ancient Siberian Lineage The evolutionary relationships between extinct and extant lineages provide important insight into species% response to environmental change. The grey wolf is among the few Holarctic large carnivores that survived the Late Pleistocene megafaunal extinctions, responding to that period%s profound environmental changes with loss of distinct lineages and phylogeographic shifts, and undergoing domestication. We reconstructed global genome-wide phylogeographic patterns in modern wolves, including previously underrepresented Siberian wolves, and assessed their evolutionary relationships with a previously genotyped wolf from Taimyr, Siberia, dated at 35 Kya. The inferred phylogeographic structure was affected by admixture with dogs, coyotes and golden jackals, stressing the importance of accounting for this process in phylogeographic studies. The Taimyr lineage was distinct from modern Siberian wolves and constituted a sister lineage of modern Eurasian wolves and domestic dogs, with an ambiguous position relative to North American wolves. We detected gene flow from the Taimyr lineage to Arctic dog breeds, but population clustering methods indicated closer similarity of the Taimyr wolf to modern wolves than dogs, implying complex post-divergence relationships among these lineages. Our study shows that introgression from ecologically diverse con-specific and con-generic populations was common in wolves% evolutionary history, and could have facilitated their adaptation to environmental change. wolf Canis lupus dog evolution hybridization volk Canis lupus pes evolucija hibridizacija true false true Angleški jezik Slovenski jezik Članek v reviji 2020-02-18 11:05:50 2020-02-18 11:05:54 2022-08-26 03:49:16 0000-00-00 00:00:00 2019 0 0 13 str. article 17328 Vol. 9 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 630*13(045)=111 2045-2322 10.1038/s41598-019-53492-9 5567654 18727432 RAZ_Pilot_Malgorzata_2019.pdf RAZ_Pilot_Malgorzata_2019.pdf 1 371DFFE084370D34BD02324A918DC83A 688650ef97cfd7f61908469d48c54b03aaaadc486726f34bc04ee11d4ebdb80c f6f66fe3-a1b8-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=130150 https://doi.org/10.1038/s41598-019-53492-9 1 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=126265 Biotehniška fakulteta 0 0 0