20.500.12556/RUL-110785 HIDROGELI Z LASTNOSTMI LEPIL OBČUTLJIVIH NA PRITISK HYDROGELS WITH CHARACTERISTICS OF PRESSURE-SENSITIVE ADHESIVES Hidrogeli so polimerni materiali, ki so sposobni absorbirati velike količine vode. Svojo obliko spreminjajo glede na spremembe v okolju, kot so sprememba pH, temperature, koncentracije soli ipd. Zaradi njihovih lastnosti so zelo razširjeni v vsakdanjem življenju, na področju medicine, kmetijstva, farmacije itd. Lepila, občutljiva na pritisk (angl. Pressure Sensitive Adhesives – PSA), se prilepijo s pritiskom prsta. Imajo zmožnost, da se držijo površine materiala, in zadostno kohezijo, da omogočajo enostavno odstranjevanje iz površine materiala brez ostankov lepila. Hidrogeli z lastnostmi lepil, občutljivih na pritisk, absorbirajo pomembno količino različnih učinkovin, ne da izgubijo svoj adhezivni značaj ali elastični modul. Najpogosteje zasledimo hidrogele z lastnostmi lepil, občutljivih na pritisk v transdermalnih sistemih (transdermalni obliži). Transdermalne obliže uporabljamo na površini kože, s tem pa se izognemo presnovi prehoda v jetra in prebavni sistem. Obliži so enostavni za uporabo, omogočajo daljše trajanje terapevtskega delovanja iz ene aplikacije in reverzibilno delovanje. Hydrogels are polymeric materials which are capable of absorbing big quantities of water. They change their shape with regards to changes in the environment, such as changes in pH, temperature, the concentration of salt, etc. Because of their characteristics, they are very widespread in everyday life in the field of medicine, agriculture, pharmacy, etc. Pressure-sensitive adhesives (PSA) are stuck by finger pressure. They have the capability to stick to the surface of the material and sufficient cohesion to enable to be removed easily from the surface of the material without any residues of glue. Hydrogels with the characteristics of pressure-sensitive adhesives absorb an important quantity of different active substances without losing their adhesive character or elastic module. Most commonly, we encounter hydrogels with the characteristics of pressure-sensitive adhesives in transdermal systems (transdermal patches). We use transdermal patches on the surface of the skin. Thus, we avoid the metabolism of transition to the liver and the digestive system. The patches are easy-to-use and enable longer duration of therapeutic action from one application and reversible action. hidrogel lepila občutljiva na pritisk transdermalni sistem hydrogel pressure-sensitive adhesives transdermal system true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2019-09-19 10:25:11 2019-09-19 10:25:13 2022-08-22 03:45:57 0000-00-00 00:00:00 2019 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 5244 1538433219 Pucelj_Martina_tina_-_HIDROGELI_Z_LASTNOSTMI_LEPIL_OBCUTLJIVIH_NA_PRITISK.pdf Pucelj_Martina_tina_-_HIDROGELI_Z_LASTNOSTMI_LEPIL_OBCUTLJIVIH_NA_PRITISK.pdf 1 F478F64DBB5CD6816B89EEF7D08B3D91 06b0ed5690536bfd89c7d048941175e3fe80aa096a0a97af4dae25a8e962d1f6 349670a2-a1b7-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=122485 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0