20.500.12556/RUL-109532 Razporeditev mikrotubulov v epitelnih celicah različnih regij prebavne cevi pri nevretenčarskih modelnih organizmih Prebavilo nevretenčarskega modelnega organizma P. scaber sestavljajo požiralnik, želodec in zadnje črevo ter prebavne žleze. Zadnje črevo delimo na tri anatomsko in funkcijsko različna področja, to so anteriorna komora, papilatna regija in rektum. Vsak del prebavila opravlja določeno funkcijo. Naloga želodca je drobljenje, sortiranje in filtriranje hrane; v anteriorni komori poteka prebava in absorpcija; v papilatni regiji pa transport ionov in reabsorpcija vode Z imunolokalizacijo smo analizirali variabilnost razporeditve mikrotubulov v epitelnih celicah različnih anatomskih regij prebavne cevi. Ugotovili smo, da je največ mikrotubulov v področju tiflosolisa in tiflosolnih gub v zadnjem delu anteriorne komore in v papilatni regiji, kjer so razporejeni v apikalnobazalnih snopih. Veliko mikrotubulov je tudi v apikalnih delih celic inferomedianuma želodca ter celic tiflosolisa in tiflosolnih gub v sprednjem in osrednjem delu anteriorne komore. V splošnem je mikrotubulov več v mehansko bolj obremenjenih delih prebavne cevi. The digestive system of the model invertebrate organism P. scaber consists of the esophagus, stomach, hindgut and digestive glands. Hindgut is divided into three anatomically and functionally distinct parts, the anterior chamber, papillate region, and rectum. Each part of the digestive system has a specific function. The stomach performs mastication, sorting and filtering of the food; in the anterior chamber digestion and absorption of nutrients take place; and in the papillate region ion transport and water reabsorption take place. We analyzed the variability of the microtubule distribution in epithelial cells of different anatomical regions of the digestive tract by immunolocalization. The results show that microtubules are most abundant in the area of typhlosolis and typhlosolic folds in the posterior region of the anterior chamber and in the papillate region, where they are arranged in the apical-basal bundles. A large number of microtubules is also present in the apical parts of cells in inferomedianum of the stomach and in typhlosolis and typhlosolic folds of the anterior and middle regions of the anterior chamber. Microtubules are in general more abundant in mechanically loaded parts of the digestive tract. Porcellio scaber anteriorna komora papilatna regija imunolokalizacija mikrotubuli epitel Porcellio scaber anterior chamber papillate region immunolocalization microtubules epithelium true false false Slovenski jezik Angleški jezik Diplomsko delo/naloga 2019-09-05 10:05:06 2019-09-05 10:05:09 2022-08-21 03:42:45 0000-00-00 00:00:00 2019 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 6470 1538316995 Medved_Ines_-_Razporeditev_mikrotubulov_v_epitelnih_celicah_razlicnih_regij_prebavne_cevi_pri_ne.pdf Medved_Ines_-_Razporeditev_mikrotubulov_v_epitelnih_celicah_razlicnih_regij_prebavne_cevi_pri_ne.pdf 1 1F4D9FBFF12B8C5081D1782500503E84 829943e8639eaa30916a6bcebbb0267417f515520aaacfc1bf33073b069c607b e398fd03-a1b6-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=121105 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0