20.500.12556/RUL-101838 Nutrigenomika in nutrigenetika. Nutrigenomics and nutrigenetics V diplomskem delu sta predstavljeni nutrigenomika in nutrigenetika. Nutrigenetika preučuje, kako lahko različice v genetskem zapisu med posamezniki spremenijo njihov fiziološki odziv na hrano, nutrigenomika pa po drugi strani preučuje neposreden in posreden vpliv komponent hrane na genom, transkriptom, proteom in metabolom, ter s tem na regulacijo izražanja genov in stabilnost DNA. Komponente hrane imajo lahko vlogo ligandov za transkripcijske faktorje ter so vključene v številne metabolne poti, s tem pa spreminjajo koncentracije substratov in intermediatov vključenih v regulacijo izražanja genov. Poleg tega lahko vplivajo na signalne poti, na posttranslacijske modifikacije proteinov, lahko pa imajo tudi vlogo koencimov ali ostalih encimskih kofaktorjev. In the thesis nutrigenomics and nutrigenetics are described. Nutrigenetics studies how genetic variants among individuals can change their physiological response to food, while nutrigenomics, on the other hand, studies the direct and indirect influence of food components on genome, transcriptome, proteome, and metabolome, thereby on the regulation of gene expression and on the stability of DNA. Food components can act as ligands for transcription factors and are included in many metabolic pathways, which causes changes in the concentrations of substrates and intermediates, involved in the regulation of gene expression. They can also affect signal pathways, posttranslational modifications of proteins and may have a role of coenzymes or other enzyme cofactors. hrana nutrigenomika nutrigenetika prehranska genomika food nutrigenomics nutrigenetics nutritional genomics true false false [K. Zevnik] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2018-07-08 07:45:56 2018-07-08 07:45:57 2022-08-15 03:38:47 0000-00-00 00:00:00 2018 0 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 60:612.39:575.113(043.2) 151507 9006457 3336.pdf 3336.pdf 1 6496EA8616AD0F590B0547BCFA72B30B f0461733ed8d9f4dc1786b9f6fe19017d2ea7dbe45d937d27032db9044f24ca2 6ab16dd6-a1b5-11eb-a523-00155dcfd717 https://repozitorij.uni-lj.si/Dokument.php?lang=slv&id=112050 Biotehniška fakulteta 0 0 0