The limits of ‘Generally Recognized As Safe’ classification for inhaled compounds in Electronic Nicotine Delivery SystemsVinko, Luka (Avtor) Devetak, Iztok (Avtor) Saksida, Tine (Avtor) Kocmut, Tjaša (Avtor) Trebše, Polonca (Avtor) Bavcon Kralj, Mojca (Avtor) Electronic Nicotine Delivery Systems (ENDS)vapeschemical analysisquestionnaireschool studentsnicotine use patternsElectronic Nicotine Delivery Systems (ENDS) liquids contain compounds deemed safe for ingestion “Generally Recognized As Safe” (GRAS), yet lack inhalation safety data, posing risks, especially to adolescents. This study analysed chemical discrepancies in ENDS via gas chromatography–mass spectrometry and surveyed Slovenian secondary students on nicotine use. Analysis revealed cytotoxic substances when inhaled and unlisted solvents, exposing a mismatch between labelled and actual content. Most adolescents who used ENDS focused only on nicotine percentage and largely ignored product composition, despite knowing nicotine is harmful. Findings stress the need for toxicological evaluation, clearer labelling, stricter regulation, and targeted youth education.20262026-07-02 07:05:20Članek v reviji184206UDK: 54ISSN pri članku: 1580-3155DOI: 10.17344/acsi.2025.9528COBISS_ID: 283174147sl