One-pot synthesis and photochemical diversification of pyrazolo[1,2-a]pyridazinones into 3D-rich scaffoldsBabnik, Ines (Avtor) Petek, Nejc (Avtor) Grošelj, Uroš (Avtor) Svete, Jurij (Avtor) Štefane, Bogdan (Avtor) atmospheric chemistryazomethinecyclizationirradiationreaction productsWe report a one-pot, three-component synthesis of pyrazolo[1,2-a]pyridazinones from tetrahydropyridazines, a transformation that was historically challenging due to competing ring contractions. The resulting compounds undergo photoinduced transformations, without the need for external photocatalysts, to afford diverse 3D-rich derivatives, including tricyclic cyclobutenes and γ-(pyrazol-1-yl)butanals. Enabled by mild conditions, this strategy offers an efficient, atom-economical route to structurally diverse pyrazolo[1,2-a]pyridazinones and their derivatives.20262026-02-19 12:17:37Članek v reviji179667UDK: 547.8:544.52ISSN pri članku: 0022-3263DOI: 10.1021/acs.joc.5c02313COBISS_ID: 268035331sl