Standard operating procedure for interferometric light microscopy of extracellular particles within the nanostructurome pipelineRomolo, Anna (Avtor) Kralj-Iglič, Veronika (Avtor) bioactive compoundsgreen productmicroalgae biomassmicroalgae sample preparationA standard operating procedure (SOP) for assessment of number density and hydrodynamic diameter of particles sized between cca 80 nm and 500 nm is presented. The aim of this SOP is to provide characterization of extracellular particles (EPs) which enables analysis of large cohorts of minimally processed samples. EPs are sub-micron-sized particles shed by all types of cells. They are free to travel to reach distant cells and can interact with them. Therefore they present an universal mechanism of cell-to-cell communication which is a subject of studies of different mechanisms underlying physiological and pathophysiological processes.20252025-07-01 13:37:16Neznano169995UDK: 502.131.1DOI: 10.55295/PSL.12.2025.III7COBISS_ID: 240977667OceCobissID: 237747715sl