Prevention and treatment of antibiotics-associated adverse effects through the use of probioticsYang, Shuwei (Avtor) Qiao, Jiaqi (Avtor) Zhang, Meng (Avtor) Kwok, Lai-Yu (Avtor) Bogovič Matijašić, Bojana (Avtor) Zhang, Heping (Avtor) Zhang, Wenyi (Avtor) probioticsantibioticsgut microbiotaintestinal barrierimmune regulationgut-brain axisBackground: The human gut hosts a diverse microbial community, essential for maintaining overall health. However, antibiotics, commonly prescribed for infections, can disrupt this delicate balance, leading to antibiotic-associated diarrhea, inflammatory bowel disease, obesity, and even neurological disorders. Recognizing this, probiotics have emerged as a promising strategy to counteract these adverse effects. Aim of review: This review aims to offer a comprehensive overview of the latest evidence concerning the utilization of probiotics in managing antibiotic-associated side effects. Key scientific concepts of review: Probiotics play a crucial role in preserving gut homeostasis, regulating intestinal function and metabolism, and modulating the host immune system. These mechanisms serve to effectively alleviate antibiotic-associated adverse effects and enhance overall well-being.20252025-05-12 10:16:43Članek v reviji169098UDK: 612.3:616ISSN pri članku: 2090-1224DOI: 10.1016/j.jare.2024.06.006COBISS_ID: 198406403sl