The effects of resistance training in patients with coronary diseaseKambič, Tim (Avtor) Lainščak, Mitja (Mentor) Hadžić, Vedran (Komentor) resistance trainingaerobic trainingcardiac rehabilitationcoronary artery diseaseResistance training (RT) in combination to aerobic training (AT) was shown to be superior when compared with AT alone, however, it remains unknown whether high load (HL-) RT provides more benefits than low load (LL-) RT in patients with coronary artery disease (CAD). This study aimed to compare the effects of HL-RT or LL-RT combined with AT versus AT alone on maximal aerobic capacity (VO2max) and maximal voluntary contraction (MVC), body composition, physical performance and physical activity, glucose metabolism, quality of life and acute hemodynamic response (heart rate and blood pressure) to resistance exercise (RE). We randomised 79 patients with CAD to HL-RT+AT (70%-80% of one repetition maximum [1-RM]), LL-RT+AT (35%–40% of 1-RM) or AT alone. Fifty-nine patients, predominately males (75%), mean (SD), 61(8) years old and mostly with preserved left ventricular ejection fraction (53 (9) %) completed the study. Measurements were performed at baseline and post-training. All training modalities were safe and improved VO2max (p <0.01), whereas only HL-RT and LL-RT modalities improved MVC (both p <0.001). HL-RT improved VO2 max to a greater extent than AT (+18%, p = 0.032). There was a greater increase in MVC following HL-RT compared with LL-RT (+7%, p = 0.018) and AT (+16 %, p <0.001), and following LL-RT compared with AT (+10%, p = 0.001). All training modalities improved most of the physical abilities, but HL-RT and LL-RT were superior to AT in gait speed, and upper and lower limb muscle strength parameters. There was no between-modalities difference in body composition, physical activity, blood lipids, insulin resistance and quality of life. The acute hemodynamic response to RE was within physiological ranges, and similar between HL-RE and LL-RE. Our findings support the implementation of HL-RT in addition to AT in cardiac rehabilitation for patients with CAD.20232023-03-29 07:15:06Doktorsko delo/naloga144991VisID: 42155COBISS_ID: 148064259sl