A comparison of analytic models for the costs of the hospitalized diabetic patientsZigon, Giulia (Avtor) Rosato, Rosalba (Avtor) Bò, Simona (Avtor) Gregori, Dario (Avtor) OBJECTIVE: To compare some survival models as applied to the estimation of thecosts of hospitalization as a function of several covariates in diabetic patients. The application of the Aalen regression model (Aalen, 1989) to medical costs is stressed. DESIGN: Retrospective observational study analyzinghospitalizations in a cohort of diabetic patients with a follow up of4.5 years. STUDY POPULATION: A total of 2550 patients have been included in the cohort, according to clinical-based enrollment standards. The patients with at least one hospitalization have been considered in this analysis. METHODS: Costs have been modelled using five different regression model: the ordinary least square regression model, the logistic regression model using the median and the third quartile of the costs distribution as cut-off points,the parametric survival model assuming Weibull distribution, the Cox proportional hazard model and the Aalen additive regression model. CONCLUSIONS: The Aalen additive regression model applied to the costs has the best performances in estimating the mean hospitalization costs for specific clinical profiles.20052014-07-11 14:26:45Delo ni kategorizirano22465sl