Scale-up of integrated care interventions for chronic diseases in diverse settingsKu, Grace Marie V (Avtor) Klemenc-Ketiš, Zalika (Avtor) Poplas-Susič, Tonka (Avtor) Remmen, Roy (Avtor) Van Damme, Win (Avtor) Wouters, Edwin (Avtor) Van Olmen, Josefien (Avtor) Klipstein-Grobusch, Kerstin (Avtor) integrated carediabetes mellitus type 2scaling-upThe global burden of chronic conditions such as Type 2 Diabetes (T2DM) and hypertension (HTN) is increasing exponentially, not only in high-income countries (HIC) but also, and more rapidly, in low- and middle-income countries (LMIC). Health systems worldwide struggle to manage this growing burden. Integrated interventions for prevention, detection, treatment, and control of T2DM and HTN have been previously demonstrated to be effective in controlled or small-scale settings [1, 2]. However, complex organisational approaches are needed to implement such interventions nationwide in a large-scale manner. These approaches require system changes and coordinated actions from many different actors and institutions to produce maximal effect. Scaling-up has proven to be challenging all around the world, producing mixed outcomes in both HICs and LMICs. Better understanding of how to address the systemic issues of scaleup is needed to develop and document strategies for sustainable and effective scale-up of such interventions. Global challenges and health system constraints urge us to think and work across contexts. Through reciprocal learning between different contexts, we can increase the understanding of the relationships between context, intervention, implementation and impact [3] for broad application of sustainable and effective scale-up models in different settings.20242026-06-02 09:11:00Članek v reviji183026sl