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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/"><rdf:Description rdf:about="https://repozitorij.uni-lj.si/IzpisGradiva.php?id=169974"><dc:title>Design, synthesis and evaluation of a novel fluorescent probe for competitive fluorescence polarization assay to screen galectin-8 inhibitors</dc:title><dc:creator>Purić,	Edvin	(Avtor)
	</dc:creator><dc:creator>Marinovich,	Marina	(Avtor)
	</dc:creator><dc:creator>Kojek,	Zala	(Avtor)
	</dc:creator><dc:creator>Kahl-Knutson,	Barbro	(Avtor)
	</dc:creator><dc:creator>Leffler,	Hakon	(Avtor)
	</dc:creator><dc:creator>Nilsson,	Ulf	(Avtor)
	</dc:creator><dc:creator>Anderluh,	Marko	(Avtor)
	</dc:creator><dc:creator>Mravljak,	Janez	(Avtor)
	</dc:creator><dc:subject>fluorescence polarisation assay</dc:subject><dc:subject>carbohydrates</dc:subject><dc:subject>lectins</dc:subject><dc:subject>galectin-8</dc:subject><dc:description>In the present work, we describe the design, synthesis and evaluation of a galectin-8-binding fluorescent probe designed for a competitive fluorescence polarization (FP) assay for screening new galectin-8N inhibitors. The probe was characterized for its photophysical properties and its binding affinity for galectin-8N was determined by using FP. We evaluated the probe in a competitive FP assay with three known galectin-8N inhibitors and demonstrated its suitability for high-throughput screening.</dc:description><dc:date>2025</dc:date><dc:date>2025-06-30 09:32:06</dc:date><dc:type>Članek v reviji</dc:type><dc:identifier>169974</dc:identifier><dc:language>sl</dc:language></rdf:Description></rdf:RDF>