Reusable Pd-polyHIPE for Suzuki–Miyaura couplingRavbar, Miha (Avtor) Koler, Amadeja (Avtor) Paljevac, Muzafera (Avtor) Krajnc, Peter (Avtor) Kolar, Mitja (Avtor) Iskra, Jernej (Avtor) palladiummixturescatalystssolventspolymersPalladium was immobilized on a highly porous copolymer of 4-vinylpyridine and divinylbenzene (polyHIPE─poly(high internal phase emulsion)) using palladium(II) acetate to obtain PolyPy-Pd with 6.1 wt % or 0.57 mmol Pd/g. The immobilized catalyst was able to catalyze the coupling of iodobenzene and phenylboronic acid in ethylene glycol monomethyl ether/water (3:1) within 4 h at rt and complete conversion was observed when 2.5 mol % of Pd per PhI was used. The reaction tolerated a wide range of substituents on the aromatic ring. Iodobenzene derivatives with electron-withdrawing substituents showed higher reactivity, while the opposite was true for the phenylboronic acid series. The polyHIPE-supported Pd catalyst was also used for the direct conversion of phenylboronic acid to biphenyl through an iodination/coupling reaction sequence. The recyclability of the heterogeneous catalyst was also optimized, and by finding a suitable combination of solvents for the loading of Pd, the reaction, and the isolation of the product, the solid-supported catalyst was completely regenerated and used in the next reaction with the same activity.20222022-05-26 14:22:03Članek v reviji136962sl