Electroporation is a phenomenon in which cell membrane permeability increases
due to cell exposure to the electric field. The electric field in the tissue is
usually established via electrodes, which are placed on the surrounding tissue.
However, when the target area is located outside of the reach of electrodes, an
invasive insertion of electrodes is required, which increases the complexity of the
electroporation therapy itself. One of the possible, but unfortunately not yet well
researched of non-invasive methods, is establishment of an electric field in tissue
using an alternating magnetic field. In this paper, a numerical model is presented
which allows the study of the magnetic flux density, the induced electric field, and
the heating of the coil due to the applied electric current. Results have been confirmed
by experimental measurements. Maximum induced electric field with used
coil design is 158 V/m and maximum magnetic flux density of 0.80 T. The coil is
heated by 15.1 +- 0.3 C when supplying 500 pulses to it. The proposed geometry
of a new coil reaches a 20 % higher magnetic flux density, however heating of the
coil is also higher.
|